Results 191 to 200 of about 38,885 (308)

Targeting Histone H3K9 Methyltransferase G9a as a Potential Therapeutic Strategy for Neuropsychiatric Disorders

Medicinal Research Reviews, EarlyView.
ABSTRACT Neuropsychiatric disorders present a multifaceted challenge, characterized by cognitive, social, and motor impairments with manifold underlying mechanisms. Recent attention has turned to epigenetic mechanisms, particularly histone lysine methyltransferases (HKMTs), such as G9a, in understanding fundamental pathogenesis.
Malak Hajar, Tobias Werner, Mihajlo Gajic, Holger Stark, Bassem Sadek   +4 more
wiley   +1 more source

Acetylation suppresses breast cancer progression by sustaining CLYBL stability. [PDF]

J Transl Med
Deng X, Ma C, Chen X, Yi M, Cao Q, Liao R, Lei X, Bai L, Zhao B, Wang Y, Shen Z, Wu L, Dong C, Dai Z.   +13 more
europepmc   +1 more source

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

Medicinal Research Reviews, EarlyView.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro, Sara Rossi, Stefania Butini, Sandra Gemma, Gabriele Carullo, Giuseppe Campiani   +5 more
wiley   +1 more source

Emerging therapeutic agents in multiple myeloma: highlights from the 2024 ASH annual meeting. [PDF]

Biomark Res
Zhang Q, Song Y, Zhou K, Lin Q.
europepmc   +1 more source

Phorbol esters stimulate spermidine/spermine N¹‐acetyltransferase activity in mitogen‐stimulated bovine lymphocytes [PDF]

, 1984
Isao Matsui‐Yuasa, Shuzo Otani, Zhao Wu Shu, Seiji Morisawa   +3 more
openalex   +1 more source

Maternal Dietary Fiber Intake During Lactation and Human Milk Oligosaccharide Fucosylation: a PRIMA Birth Cohort Study

Molecular Nutrition &Food Research, EarlyView.
Healthy breastfeeding women were recruited within the prospective birth cohort PRIMA. We collected a fresh human milk sample at 1 month postpartum to assess relative human milk oligosaccharide (HMO), HMO‐bound fucose levels, and secretor status. In univariate and multivariate linear regression analysis, we did not observe an association between ...
Anneke H. Hellinga, Samanta Cajic, Hanneke F. Linde, Arthur H. van Stigt, Jeanne H. M. de Vries, Elske M. Brouwer‐Brolsma, René Hennig, Erdmann Rapp, Marko Mank, Bernd Stahl, Aletta D. Kraneveld, Jeanette H. W. Leusen, Louis Bont, Belinda van't Land, the PRIMA group   +14 more
wiley   +1 more source

smu_1558c-mediated regulation of growth and biofilm formation in Streptococcus mutans. [PDF]

Front Microbiol
Zhou J, Ma Q, Liang J, Pan Y, Chen Y, Yu S, Liu Y, Zhang Q, Li Y, Zou J.   +9 more
europepmc   +1 more source

Effects of postnatal hypoxia-ischemia on cholinergic neurons in the developing rat forebrain: choline acetyltransferase immunocytochemistry [PDF]

, 1987
Michael V. Johnston, Christopher J. Hudson   +1 more
openalex   +1 more source

A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury

Neuroprotection, EarlyView.
This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley   +1 more source

Histone Acetylation in Central and Peripheral Nervous System Injuries and Regeneration: Epigenetic Dynamics and Therapeutic Perspectives. [PDF]

Int J Mol Sci
Palomés-Borrajo G, Navarro X, Penas C.
europepmc   +1 more source