Results 201 to 210 of about 91,412 (386)

EP300 Modulates MCM8 Transcription and Augments the Malignant Phenotype of Hepatitis B Virus–Positive Hepatocellular Carcinoma Cells

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Chronic infection with the hepatitis B virus (HBV) remains one of the primary drivers of the development of hepatocellular carcinoma (HCC), a highly aggressive malignancy with a grim prognosis. This study focused on the role of E1A‐binding protein p300 (EP300) in the malignant phenotype of HBV‐positive HCC cells and its functional mechanism ...
Fang Xue, Tian‐Feng Sun
wiley   +1 more source

Sensory and Autonomic Fibers in Anterior Ethmoid, Posterior Nasal, Posterolateral Nasal Nerves

open access: yesThe Laryngoscope, EarlyView.
All cadaveric anterior ethmoid, posterior, and posterolateral nasal nerves contained roughly equivalent proportions of sensory, parasympathetic, and sympathetic nerve fiber markers. Neurokinin A was the only neuropeptide with consistently greater percent areas across the different nasal nerves.
John R. Craig   +6 more
wiley   +1 more source

Function and expression of N-acetyltransferases 1 and 2 are altered in lymphocytes in type 2 diabetes and obesity

open access: yesBiochemistry and Biophysics Reports
The cytosolic enzymes N-Acetyl Transferases 1 and 2 (NATs) transfer an acetyl group from acetyl-CoA to a xenobiotic substrate. NATs are regulated at the genetic and epigenetic levels by deacetylase enzymes such as sirtuins.
Víctor Alejandro Paz-Rodríguez   +10 more
doaj  

Magnetic Levitational Assembly of Differentiated SH‐SY5Y Cells for Aβ‐Induced 3D Alzheimer's Disease Modeling and Curcumin Screening

open access: yesMacromolecular Bioscience, EarlyView.
This study explores the 3D modeling of Alzheimer's disease using differentiated SH‐SY5Y spheroids via Magnetic levitation (MagLev) and investigates the neuroprotective effect of Curcumin. Differentiated spheroids displayed high viability and significant neuronal characteristics. Aβ 1‐42 exhibited neurotoxic effects on differentiated spheroids. Curcumin
Rumeysa Bilginer‐Kartal   +1 more
wiley   +1 more source

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