Development of coumarin-sulfonate scaffolds for cholinesterase inhibition: experimental and computational studies toward Alzheimer's disease therapy. [PDF]
RSC AdvMughal EU +9 more
europepmc +1 more source
Community Dentistry and Oral Epidemiology, EarlyView.ABSTRACT Objective To evaluate the prospective association between the absence and different models of primary oral health care in Brazil (traditional units and Family Health Strategy [FHS] teams) and preventive dental visits and risk behaviours (smoking initiation and increase in alcohol consumption) among young individuals.
Jocelaine Vieira Vione +5 more
wiley +1 more source
Computational evaluation of carnosic acid as a 4EY7 inhibitor for potential anti-Alzheimer therapy. [PDF]
Front Aging NeurosciAlhamyani A.
europepmc +1 more source
Adherence to Treatment in Allergic Rhinitis During the Pollen Season in Europe: A MASK‐air Study
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 226-238, March 2025.In a study assessing mobile health data, (i) adherence to rhinitis medication was highest for oral antihistamines and lowest for azelastine‐fluticasone, (ii) in weeks of partial adherence, azelastine‐fluticasone was associated with lower levels of reported rhinitis symptoms than other medication classes.
Bernardo Sousa‐Pinto +121 more
wiley +1 more source
Evaluation of the Insecticidal Activity, Formulation, and Computational Study of Some Hydrazone and Pyridazin-3(2H)-one Derivatives. [PDF]
Chem BiodiversIsmail MF +5 more
europepmc +1 more source
Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions
Clinical Endocrinology, EarlyView.ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley +1 more source
Discovery of <i>Caralluma</i>-derived pregnane glycosides as potent and selective cholinesterase inhibitors: integrated <i>in silico</i> and <i>in vitro</i> evaluation. [PDF]
RSC AdvAl-Karmalawy AA +6 more
europepmc +1 more source
Child &Family Social Work, EarlyView.ABSTRACT There is a critical public health crisis regarding the infant mortality rate between black and white mothers in the USA. This issue is more pronounced in North Carolina, where black infants have a much higher infant mortality rate than whites.
Jeffrey Shears +7 more
wiley +1 more source
Bridging the gap in Alzheimer's therapy: strategic design and SAR evolution of coumarin-based hybrids as potent MTDLs. [PDF]
RSC AdvEl-Mokaddem OK +3 more
europepmc +1 more source
Neurodevelopmental Phenotypes and Brain Anomalies in Individuals With Heterozygous SEMA6A Variants
Clinical Genetics, EarlyView.SEMA6A plays a role in cell migration and axon guidance in the developing central nervous system. Phenotypes seen in eleven individuals heterozygous for SEMA6A variants included developmental delay, intellectual disability, autism/autistic behaviors, behavioral abnormalities, attention disorders, hypotonia, and brain anomalies.
Evan Burchfiel +27 more
wiley +1 more source