Foxg1 and Retinoic Acid Signaling Regulate Zonal Patterning in the Developing Olfactory Epithelium
ABSTRACT Odor information processing begins in the olfactory epithelium (OE), which in mice is spatially divided into two zones: the dorsomedial zone (D‐zone), responsible for innate aversive behaviors, and the ventrolateral zone (V‐zone), associated with learning‐dependent behaviors.
Anzu Kuriyama, Carina Hanashima
wiley +1 more source
Design, Synthesis, and Evaluation of 1-Benzylpiperidine and 1-Benzoylpiperidine Derivatives as Dual-Target Inhibitors of Acetylcholinesterase and Serotonin Transporter for Alzheimer's Disease. [PDF]
González-Gutiérrez JP+12 more
europepmc +1 more source
ABSTRACT Introduction To evaluate the prevalence and potential risk factors of work‐related musculoskeletal disorders (WMSDs) among fifth‐year dental students from Romania, Türkiye, Serbia, North Macedonia and Montenegro. Materials and Methods A prospective questionnaire‐based survey was conducted, including demographics, the Nordic Musculoskeletal ...
Özlem Daltaban+8 more
wiley +1 more source
Accelerating countermeasure candidate discovery for A-series chemical warfare agent exposure. [PDF]
Morato NM+7 more
europepmc +1 more source
Abstract Febrile infection–related epilepsy syndrome (FIRES) is a rare clinical presentation of refractory status epilepticus following a febrile infection. This study analyzes data from the NORSE/FIRES Family Registry, an international web‐based registry available in six languages with data entered by patients, families, and clinicians to explore ...
Karnig Kazazian+8 more
wiley +1 more source
Multitarget Compounds Designed for Alzheimer, Parkinson, and Huntington Neurodegeneration Diseases. [PDF]
Katsoulaki EE+2 more
europepmc +1 more source
ABSTRACT Introduction The first signs of mental health issues in dentistry manifest as early as undergraduate training, thus it is essential to delve into the concept of resilience to equip those studying and working in dentistry with the resources to cultivate a positive mindset.
Vaida Kaunaite, Marina Harris
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Synthesis, Biological Evaluation, and In Silico Characterization of Novel Imidazothiadiazole-Chalcone Hybrids as Multi-Target Enzyme Inhibitors. [PDF]
Alici H+4 more
europepmc +1 more source
Retraction of "Design, Synthesis, and Biological Evaluation of Notopterol Derivatives as Triple Inhibitors of AChE/BACE1/GSK3β for the Treatment of Alzheimer's Disease". [PDF]
Wang N+13 more
europepmc +1 more source
Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder+4 more
wiley +1 more source