Results 51 to 60 of about 61,991 (198)

Perfectionism and School Non‐Attendance Reasons in Adolescents: A Latent Profile Analysis

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Limited prior knowledge exists regarding perfectionism and other relevant educational variables, such as the wide spectrum of School Attendance Problems. However, perfectionism has been related to somatic complaints and symptoms, school burnout, and negative emotionality. Therefore, this study analyzes the association between this
Andrea Fuster, María Vicent, María Pérez‐Marco, Carolina Gonzálvez   +3 more
wiley   +1 more source

Characterization of the Fifth Putative Acetylcholinesterase in the Wolf Spider, Pardosa pseudoannulata

Molecules, 2017
Background: Acetylcholinesterase (AChE) is an important neurotransmitter hydrolase in invertebrate and vertebrate nervous systems. The number of AChEs is various among invertebrate species, with different functions including the ‘classical’ role in ...
Xiangkun Meng, Xixia Xu, Haibo Bao, Jianjun Wang, Zewen Liu   +4 more
doaj   +1 more source

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

Journal of Applied Toxicology, EarlyView.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos, Jéssica Natalia Barbosa de Almeida, Camila Cavalleiro Frias, Wanda Pereira Almeida, Edson Luis Maistro   +4 more
wiley   +1 more source

Developmental dynamics of symptoms of emotional problems in childhood and adolescence: A longitudinal network analysis

JCPP Advances, EarlyView.
This study examined how emotional symptoms co‐develop from childhood to adolescence using longitudinal data from over 11,000 children and adolescents. Network analyses revealed reciprocal links between core symptoms of anxiety and depression, with no significant differences between males and females.
Eira R. Aksnes, Marianne Skogbrott Birkeland, Omid V. Ebrahimi, Mona Bekkhus, Lia Ferschmann, Dani Beck, Trude Fixdal, Alexandra Havdahl, Lydia Gabriela Speyer, Lars T. Westlye, Marieke G. N. Bos, Christian K. Tamnes   +11 more
wiley   +1 more source

El genocidio aché: de la protección internacional a la jurisdicción universal

Revista de Estudios sobre Genocidio, 2020
El genocidio aché es un caso paradigmático de exterminio de un pueblo indígena americano en el marco de procesos de colonización del siglo XX. Su tratamiento en el marco de los sistemas internacionales de protección de derechos humanos y en las medidas ...
Hugo Valiente
doaj  

Irritability in preschool children with attention‐deficit/hyperactivity disorder: Analysis of family environmental factors

JCPP Advances, EarlyView.
Abstract Background Irritability affects one‐third of children and adolescents with attention‐deficit/hyperactivity disorder (ADHD) and is associated with negative outcomes. The family environment plays a prominent role in the child's development, and therefore on the risk for irritability, especially during the preschool period.
Analin Ono Baraniuk, Giovanni Abrahão Salum, David Daley, Erika Mendonça de Morais, Filipe Jaeger Zabala, Luiz Eduardo de Souza, Guilherme V. Polanczyk, Luisa Shiguemi Sugaya   +7 more
wiley   +1 more source

Model acetylcholinesterase‐Fc fusion glycoprotein biotechnology system for the manufacture of an organophosphorus toxicant bioscavenging countermeasure

Bioengineering & Translational Medicine
Organophosphate (OP) toxicants remain an active threat to public health and to warfighters in the military. Current countermeasures require near immediate administration following OP exposure and are reported to have controversial efficacies ...
Thomas G. Biel, Talia Faison, Alicia M. Matthews, Uriel Ortega‐Rodriguez, Vincent M. Falkowski, Edward Meek, Xin Bush, Matthew Flores, Sarah Johnson, Wells W. Wu, Mari Lehtimaki, Rong‐Fong Shen, Cyrus Agarabi, V. Ashutosh Rao, Janice E. Chambers, Tongzhong Ju   +15 more
doaj   +1 more source

Inhibition of Muscle-Specific Protein Kinase (MuSK) Releases Organophosphate-Aged Acetylcholinesterase (AChE) from C2C12 Cells

Toxics
Mechanistically, OPs inhibit acetylcholinesterase (AChE), an enzyme that terminates cholinergic transmission, triggering a sustained activation of acetylcholine receptors.
Monica Moncada-Restrepo, Sarah Eysoldt, Jeronimo Medina, Valentina Di Guida, Jeremy W. Chambers   +4 more
doaj   +1 more source

Updated ERNICA guidelines for the management of rectosigmoid Hirschsprung's disease 2025

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives To revise the 2018 European Reference Network for rare Inherited and Congenital Digestive and Gastrointestinal Anomalies (ERNICA) clinical guideline for the management of rectosigmoid Hirschsprung's disease (HSCR) based on new evidence and evolving clinical priorities, ensuring continued relevance, trustworthiness, and consistency ...
Daniel Rossi, Willemijn Irvine, Anna Löf Granström, Annika Mutanen, Roel Bakx, Kristin Bjørnland, Duccio Cavalieri, Piotr Czauderna, Anne Dariel, Mark Ellebæk, Francesco Fascetti Leon, Fabio Fusaro, Dirk‐Jan Gloudemans, Marietta Jank, Peter Kolja Kvist, Martin Lacher, Annette Lemli, Lucas Matthyssens, Louise Montalva, Pedro Palazon, Alessio Pini Prato, Lucie Pos, Roxana Rassouli‐Kirchmeier, Konrad Reinshagen, Nagoud Schukfeh, Rony Sfeir, Olivia Spivack, Pernilla Stenström, Lovisa Telborn, Eelke Toxopeus, Alejandra Vilanova, Miriam Wilms, Rene Wijnen, Cornelius E. J. Sloots, Mikko Pakarinen, Tomas Wester   +35 more
wiley   +1 more source

Differential Inhibition of the Brain Acetylcholinesterase Molecular Forms Following Sarin, Soman and VX Intoxication in Laboratory Rats

Acta Medica, 1997
The female Wistar rats were intoxicated (i.m.) with sarin, soman and VX in doses equal to 1xLD50 and pontomedullar areas of the brain were prepared, homogenized, centrifuged and in these samples, acetylcholinesterase (AChE, EC 3.1.1.7) activities were ...
Jiří Bajgar
doaj   +1 more source