Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Simple and Multiple Relationship between Self-efficacy, Achievement Goals, and Achievement Motivation in Predicting Academic Achievement among Students of Semnan University of Medical Sciences [PDF]
Introduction: Academic performance in each society reflects the educational system’s success in targeting and paying attention to meet individual needs.
afzal akbari balootbangan
doaj
Achievement Goals, Learning Strategies and Language Achievement among Peruvian High School Students
We used an achievement goal framework to study the role of motivation in the academic context of a Peruvian sample of 8th to 10th grade high school students (N = 1505).
Lennia Matos +2 more
doaj +1 more source
Academic and social goals in adolescence: developments and directions. [PDF]
Over the past fifteen years there has been an increased research interest in motivation in learning contexts. Research in the field has been lead by those working with motivational goal theory, which emphasises the reasons students engage in achievement ...
Mansfield, C.
core
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A meta-analysis of self-reported achievement goals and nonself-report performance across three achievement domains (work, sports, and education). [PDF]
During the past three decades, the achievement goal approach to achievement motivation has emerged as an influential area of research, and is dedicated to understanding the reasons behind the individual's drive to achieve competence and performance ...
Nico W Van Yperen +2 more
doaj +1 more source
Motivational goals: a cross sectional perspective [PDF]
This paper presents preliminary findings from a cross sectional study of student motivation in West Australian secondary schools. Increasingly researchers using Goal Theory have been investigating how both academic and social goals are significant to ...
Mansfield, C.
core
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The achievement goal perspective highlights the importance of mastery-approach goals in facilitating students’ academic achievement. However, a socio-ecological lens would suggest that the effectiveness of these mastery-approach goals might vary across ...
Yikang Chen +2 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source

