Results 91 to 100 of about 26,776 (221)

Serum Advanced Glycation End Products as Drivers of Poor Tendon Outcomes in Diabetes? An Emerging Hypothesis and Narrative Review

open access: yesEndocrinology, Diabetes &Metabolism, Volume 9, Issue 4, July 2026.
Tendon injuries in diabetes heal poorly, with unclear drivers of extracellular matrix disruption and altered mechanics. This narrative review synthesizes in vitro, animal, and human studies, highlighting serum advanced glycation end products as potential systemic contributors.
Eric J. Gutierrez   +3 more
wiley   +1 more source

Delay in Diagnosis of Classical Homocystinuria

open access: yesJIMD Reports, Volume 67, Issue 4, July 2026.
ABSTRACT Classical homocystinuria (HCU) is an autosomal recessive disorder of methionine metabolism with a wide spectrum of severity and clinical presentation. Timely diagnosis facilitates prompt initiation of treatment, which reduces complications. Our aim was to identify the nature of the first clinical manifestation and time to subsequent diagnosis ...
Subadra Wanninayake   +5 more
wiley   +1 more source

Don’t Underestimate Pain on Palpation in the Clinical Exam for Achilles Tendinopathy

open access: yesInternational Journal of Sports Physical Therapy
# Background Midportion Achilles tendinopathy is a common injury affecting individuals across various activity levels, characterized by pain, impaired performance, and pathological changes in tendon structure. Although the clinical examination is crucial
Andy K Smith   +4 more
doaj   +1 more source

The Composite Radial Forearm Free Flap for Tibialis Anterior Tendon Reconstruction: A Case Report

open access: yesMicrosurgery, Volume 46, Issue 5, July 2026.
ABSTRACT Distal leg reconstruction is particularly challenging due to limited local options. This challenge is accentuated when there is a concurrent tendon rupture and threatened hardware, making soft tissue coverage crucial for preserving limb function.
Stephanie E. Shin   +7 more
wiley   +1 more source

Emerging Upper Extremity Muscle Ultrasound Patterns as a Diagnostic Aid in TTN‐Related Myopathies

open access: yesMuscle &Nerve, Volume 74, Issue 1, Page 111-120, July 2026.
ABSTRACT Introduction/Aims Biallelic pathogenic variants in TTN cause rare forms of early‐onset myopathy, manifesting with variable severity, distribution, and progression of muscle weakness, often associated with respiratory insufficiency and potentially cardiomyopathy. The large size of TTN and phenotypic heterogeneity in TTN‐related myopathy (TTN‐RM)
Abigail Potticary   +3 more
wiley   +1 more source

Efficacy of Active Exercises to Improve Range of Motion in Knee Joint After Total Knee Arthroplasty. A Randomized Controlled Trial

open access: yesPhysiotherapy Research International, Volume 31, Issue 3, July 2026.
ABSTRACT Background and Purpose After total knee arthroplasty (TKA), not everybody gains a sufficient joint mobility. The objective of this study was to investigate the effects of high‐frequency (HF) versus low‐frequency (LF) self‐managed knee flexion exercises in individuals with reduced flexion after a TKA.
Lisbeth Mogensen   +3 more
wiley   +1 more source

Architecture of lower leg muscles in children: Reference curves and potential mechanisms of growth

open access: yesJournal of Anatomy, Volume 249, Issue 1, Page 54-67, July 2026.
Muscle architecture (physiological cross‐sectional area, fascicle lengths and pennation angle) was measured from multimodal MRI scans of the lower legs of 197 children aged ≤15 years. We showed that lower leg muscle volumes (product of PCSA and fascicle length) increase primarily through increases in PCSA (transverse growth) rather than increases in ...
Brian V. Y. Chow   +12 more
wiley   +1 more source

Exercise Training Stimulates the Release of Glutathione Peroxidase 1 (GPX1)‐Enriched Extracellular Vesicles That Promote Angiogenesis

open access: yesThe FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Exercise Training Stimulates the Release of Glutathione Peroxidase 1 (GPX1)‐Enriched Extracellular Vesicles that Promote Angiogenesis. The results from this study suggest that EVs isolated from blood immediately after the last bout of endurance exercise training (ExerV) are enriched in antioxidants. ExerVs stimulate vascular growth both in vitro and in 
Alexander M. Fliflet   +23 more
wiley   +1 more source

Multimaterial Triphasic Scaffold Replicates Enthesis Microenvironment to Modulate Early Cell Responses

open access: yesAdvanced NanoBiomed Research, Volume 6, Issue 6, June 2026.
A bioinspired triphasic scaffold integrating 3D printed polycaprolactone and electrospun poly(lactic‐co‐glycolic acid) is developed to replicate the organization of the tendon‐to‐bone enthesis. Cyclic mechanical stimulation induces spatially defined cell morphology and lineage‐related gene expression in human mesenchymal stem cells, highlighting the ...
Ginevra Pegollo   +7 more
wiley   +1 more source

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