Results 101 to 110 of about 123,866 (247)

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Direct repair of the chronic ochronotic Achilles tendon rupture: a case report

BMC Musculoskeletal Disorders
Background Alkaptonuria (AKU) is a rare hereditary disease. Ochronotic arthropathy, tendinopathy, and osteopenia/osteoporosis are generally musculoskeletal manifestations in patients with AKU.
Takuji Yokoe, Makoto Nagasawa, Takuya Tajima, Nami Yamaguchi, Tomomi Ota, Yudai Morita, Etsuo Chosa   +6 more
doaj   +1 more source

Transverse tendon stiffness is reduced in people with Achilles tendinopathy: A cross-sectional study.

PLoS ONE, 2019
ObjectivesThe objective of the current cross-sectional study was to examine Achilles tendon transverse stiffness in a group of recreational runners with Achilles tendinopathy, in comparison to an asymptomatic group of runners with similar training ...
Evan Finnamore, Charlotte Waugh, Lyndal Solomons, Michael Ryan, Christopher West, Alexander Scott   +5 more
doaj   +1 more source

Gastrocnemius muscle properties in children with cerebral palsy: An exploratory cross‐sectional study of variability in gastrocnemius properties

Experimental Physiology, EarlyView.
Abstract Muscle strength is a key predictor of physical functioning, yet the influence of patient and treatment factors on muscle properties in young people with cerebral palsy is not fully known. We explored whether medial gastrocnemius properties vary by age, ambulatory status and spasticity treatment (botulinum toxin or selective dorsal rhizotomy ...
Elizabeth R. Boyer, Christiana J. Raymond‐Pope, Daniel B. Hoffman, Marshall H. Taniguchi, Tom F. Novacheck, Braydon A. Crum, Peter D. Kim, Sarah M. Greising   +7 more
wiley   +1 more source

Caloric restriction and aerobic exercise differentially counteract muscle–tendon dysfunction following diet‐induced obesity in C57BL/6J mice

The Journal of Physiology, EarlyView.
Abstract figure legend Diet‐induced obesity induced fibro‐adipogenic remodelling of the muscle–tendon unit, characterized by increased fibrosis, reduced specific force, impaired relaxation kinetics, elevated hysteresis, and reduced aerobic capacity and glucose tolerance.
Leonardo Cesanelli, Petras Minderis, Andrej Fokin, Aivaras Ratkevicius, Ingrida Balnyte, Polzonetti Valeria, Tomas Venckunas, Cameron Hill, Danguole Satkunskiene, Hans Degens   +9 more
wiley   +1 more source

Incidental walking activity is sufficient to induce time-dependent conditioning of the Achilles tendon

, 2009
The Achilles tendon has been seen to exhibit time-dependent conditioning when isometric muscle actions were of a prolonged duration, compared to those involved in dynamic activities, such as walking.
Wearing, S.C., Grigg, Nicole, Stevenson, Nathan, Stevenson, N.J., Smeathers, J.E., Smeathers, James E., Wearing, Scott C., Grigg, N.L., Nicole L. Grigg, Scott C. Wearing, Nathan J. Stevenson, James E. Smeathers   +11 more
core   +1 more source

Knockdown of mitotically associated long non‐coding RNA dysregulates endothelial functions, transcriptome and proteome

The Journal of Physiology, EarlyView.
Abstract figure legend Downregulation of mitotically associated long non‐coding RNA (MANCR) disturbs transcriptome and proteome in endothelial cells, possibly leading to endothelial and vascular dysfunction in preeclampsia. Abstract Preeclampsia (PE) is a hypertensive disorder during pregnancy, which is characterized by a wide spectrum of endothelial ...
Si‐Yan Zhang, Chi Zhou, Jing Zheng
wiley   +1 more source

Mid-term Follow-up Outcomes of Minimally Invasive Paratenon Protection Repair of Ruptured Achilles Tendon

Foot & Ankle Orthopaedics
Research Type: Level 3 - Retrospective cohort study, Case-control study, Meta-analysis of Level 3 studies Introduction/Purpose: The paratenon, a protective sheath surrounding the Achilles tendon, has been shown to facilitate tendon healing.
Jian Tian MD
doaj   +1 more source

Plantarflexion maximal torque and Achilles tendon properties.

, 2016
Plantarflexion maximal torque and Achilles tendon properties.
Florian Rieder (222306), Hans-Peter Wiesinger (3159939), Alexander Kösters (3159942), Erich Müller (700839), Olivier R. Seynnes (3159945)   +4 more
core   +1 more source

Musculoskeletal Phenotypes of 19 Patients With X‐Linked HNRNPH2‐Related Neurodevelopmental Disorder: A Prospective Case Series

American Journal of Medical Genetics Part A, Volume 200, Issue 12, Page 2708-2718, December 2026.
ABSTRACT Detailed clinical phenotypes have been previously reported for 33 individuals with X‐linked HNRNPH2‐related neurodevelopmental disorder. Of these, 75% self‐reported a musculoskeletal abnormality, including hip dysplasia, scoliosis, kyphosis, lordosis, pes planus, arthritis, and missing spinous processes.
Ambar Garcia, Rachel Salazar, Nicole Holuba, Franklin E. Paulino, Michael G. Vitale, Jennifer M. Bain, Joshua Hyman   +6 more
wiley   +1 more source