Results 151 to 160 of about 65,454 (324)

Weighted cart pull: A novel outcome measure for sustained motor function in mice

open access: yesExperimental Physiology, EarlyView.
Abstract Sarcopenia, the pathological age‐related decline in muscle mass and strength, compromises independence and quality of life in older adults. Currently, no effective treatments are available. To enhance translational research using aged mouse models, we developed and validated the weighted cart pull (WCP) as a novel assessment of sustained motor
Charles D. Brennan   +12 more
wiley   +1 more source

Oedema and fatty degeneration of the soleus and gastrocnemius muscles on MR images in patients with achilles tendon abnormalities [PDF]

open access: yes, 2018
Objective: The purpose of this study was to evaluate the frequency of oedema and fatty degeneration of the soleus and gastrocnemius muscles in patients with Achilles tendon abnormalities.
Buck, Florian   +5 more
core  

Use of transcutaneous spinal cord stimulation to explore inhibitory and facilitatory circuits in muscles of the human lower limb

open access: yesExperimental Physiology, EarlyView.
Abstract The aim of this study was to explore the primary afferent depolarization mechanism, to determine whether the soleus transspinal evoked potential (TEP), elicited through transcutaneous spinal cord stimulation over the L1–L2 level, is modulated by presynaptic inhibition and heteronymous facilitation, similar to the Hoffmann (H) reflex, elicited ...
Julia Sordet   +5 more
wiley   +1 more source

Contact area, pressure distribution and mechanical stability in external arthrodesis of the ankle joint [PDF]

open access: yes, 2009
The ankle joint is often affected by arthritis, giving a joint that is painful, stiff, and restricts movement. This can result in a huge loss of mobility for the sufferer.
Connor, Chris   +2 more
core  

Activity‐induced conversion from dendritic filopodia to spines mediated by NMDA receptor‐dependent calcium transients and vesicular exocytosis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram of the conversion of dendritic filopodium into spine. Inactivation‐induced filopodia contain NMDA receptors along with recycling endosomes and microtubules. Glycine stimulation facilitates the occurrence of calcium influx through NMDA receptors, causing exocytosis of recycling endosomes via a VAMP‐dependent ...
Hui‐Jing Liu   +5 more
wiley   +1 more source

Glycosaminoglycans influence regional mechanics in young but not old Achilles tendons

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Glycosaminoglycans (GAGs) are long, polysaccharide chains that are located between collagen fibrils in tendon and decrease with age in many musculoskeletal tissues. Yet, it is unknown whether declines in GAGs with age are responsible for age‐related changes to Achilles tendon mechanics.
Jonathon L. Blank   +2 more
wiley   +1 more source

Chronic Achilles Tendon Overuse Injury: Complications after Surgical Treatment [PDF]

open access: bronze, 2000
Mika Paavola   +4 more
openalex   +1 more source

Load and muscle‐dependent changes in triceps surae motor unit firing properties in individuals with non‐insertional Achilles tendinopathy

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Motor unit firing properties of the medial gastrocnemius (MG), lateral gastrocnemius (LG), and soleus (SO) muscles were assessed using high‐density surface electromyography (HD‐sEMG) during isometric plantarflexion contractions at 10%, 40%, and 70% maximal voluntary contraction (MVC) in individuals with non‐insertional Achilles ...
Ignacio Contreras‐Hernandez   +5 more
wiley   +1 more source

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