Results 11 to 20 of about 11,829 (225)

Potentiated virucidal activity of pomegranate rind extract (PRE) and punicalagin against Herpes simplex virus (HSV) when co-administered with zinc (II) ions, and antiviral activity of PRE against HSV and aciclovir-resistant HSV [PDF]

PLoS ONE, 2017
Background There is a clinical need for new therapeutic products against Herpes simplex virus (HSV). The pomegranate, fruit of the tree Punica granatum L, has since ancient times been linked to activity against infection. This work probed the activity of
Bugert, Joachim J., Denyer, Stephen P., Heard, Charles M., Houston, David M. J.   +3 more
core   +7 more sources

PEPtalk2: results of a pilot randomised controlled trial to compare VZIG and aciclovir as postexposure prophylaxis (PEP) against chickenpox in children with cancer. [PDF]

Archives of Disease in Childhood, 2018
OBJECTIVE: To determine the likely rate of patient randomisation and to facilitate sample size calculation for a full-scale phase III trial of varicella zoster immunoglobulin (VZIG) and aciclovir as postexposure prophylaxis against chickenpox in children
Baker, S, Bate, J, Breuer, J, Chisholm, JC, Gray, J, Hambleton, S, Heath, PT, Houlton, A, Jit, M, Lowis, S, Makin, G, O'Sullivan, C, Patel, SR, Phillips, R, Ramsay, ME, Ransinghe, N, Skinner, R, Wheatley, K   +17 more
core   +7 more sources

Acute tubulointerstitial nephritis following aciclovir treatment for chickenpox in children with nephrotic syndrome – a report of two cases [PDF]

Central European Journal of Immunology, 2020
Tubulointerstitial nephritis (TIN) is an inflammatory process primarily involving the renal interstitium and is the cause of acute kidney injury (AKI) in 3-7% of cases confirmed by renal biopsy in children.
Małgorzata Pańczyk-Tomaszewska, Elżbieta Kuźma-Mroczkowska, Piotr Skrzypczyk, Hanna Szymanik-Grzelak, Jadwiga Małdyk   +4 more
openalex   +3 more sources

Aciclovir‐resistant herpes keratitis [PDF]

Clinical & Experimental Ophthalmology, 2010
AbstractHerpes simplex virus (HSV) keratitis is a common cause of ocular morbidity. Resistance to aciclovir is probably under recognized. We describe three cases of aciclovir‐resistant herpes simplex virus keratitis treated with systemic foscarnet and present a review of the pharmacological options available to manage this condition.
Keat Choong, Nathan J. Walker, Andrew Apel, Michael Whitby   +3 more
openalex   +5 more sources

A UHPLC–MS/MS Method for Therapeutic Drug Monitoring of Aciclovir and Ganciclovir in Plasma and Dried Plasma Spots

Biomedicines, 2021
The role of therapeutic drug monitoring (TDM) of valaciclovir (VA)/aciclovir (A) and valganciclovir/ganciclovir (VG/G) in critically ill patients is still a matter of debate.
Federica Pigliasco, Alessia Cafaro, Raffaele Simeoli, Sebastiano Barco, Alberto Magnasco, Maura Faraci, Gino Tripodi, Bianca Maria Goffredo, Giuliana Cangemi   +8 more
doaj   +2 more sources

A randomised controlled trial of the use of aciclovir and/or prednisolone for the early treatment of Bell's palsy: the BELLS study

Health Technology Assessment, 2009
Objective: To determine whether oral prednisolone or aciclovir, used separately or in combination, early in the course of Bell’s palsy, improves the chances of recovery at 3 and 9 months. Design: A 2 × 2 factorial randomised double-blind trial.
Frank Sullivan, IR Swan, Peter T. Donnan, JM Morrison, Blair H. Smith, Brian McKinstry, RJ Davenport, Luke Vale, Jan Clarkson, Rodolfo Hernández, Kirsty Stewart, Vicky Hammersley, Sima Hayavi, Anne McAteer, David Gray, F. Daly   +15 more
openalex   +2 more sources

Graded challenge in an aciclovir allergic patient [PDF]

Sexually Transmitted Infections, 2001
An immunocompetent woman presented with a hypersensitivity skin reaction following suppressive therapy with aciclovir for recurrent culture proved genital herpes simplex virus infection. She developed a similar reaction when treatment was changed to famciclovir. Without antiviral suppression her recurrences were frequent and distressing.
M Kawsar
openalex   +4 more sources

Eficacia del ganciclovir tópico como alternativa terapéutica de la queratitis epitelial herpética [PDF]

Revista Mexicana de Oftalmología, 2014
ResumenObjetivoComparar el uso del ganciclovir con el del aciclovir, usados de forma tópica, para la curación de la queratitis epitelial herpética en menos de 7 días.Materiales y métodosSe diseñó un ensayo clínico aleatorizado comparativo de pacientes ...
Rodríguez-García, Alejandro, Torres-Gómez, Jaime, Álvarez-Guzmán, Carlos   +2 more
core   +4 more sources

Aciclovir no tratamento da varicela em idade pediátrica: Revisão baseada na evidência

Revista Portuguesa de Medicina Geral e Familiar, 2009
Objectivos: A varicela é uma doença benigna que afecta sobretudo as crianças, sendo a taxa de incidência em Portugal (2005) de 2,37%.Apesar de auto-limitada, é altamente contagiosa e podem ocorrer complicações em 5-10% de todos os indivíduos afectados.
Tânia Colaço, Maria Espírito
openalex   +4 more sources

Antiviral activity of the organic germanium complex with aciclovir against herpes simplex virus (Herpesviridae: Alphaherpesvirinae: Simplexvirus: Human alphaherpesvirus 1/2) in the in vitro and in vivo systems

Вопросы вирусологии, 2021
Introduction. A significant increase in the incidence of various forms of herpesvirus infection (HVI) determines the need to search for new approaches to the modification of one of the basic antiviral drugs aciclovir (ACV) and its dosage forms to improve
L. M. Alimbarova, I. V. Ambrosov, S. K. Matelo, I. F. Barinsky   +3 more
doaj   +2 more sources