Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Cerebrospinal fluid and arterial acid-base equilibria in spontaneously breathing third-trimester pregnant women. [PDF]
Br J Anaesth, 2022 Zadek F +10 more
europepmc +1 more source
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Interfacial Acid-Base Equilibria and Electric Fields Concurrently Probed by <i>In Situ</i> Surface-Enhanced Infrared Spectroscopy. [PDF]
J Am Chem Soc, 2021 Delley MF, Nichols EM, Mayer JM.
europepmc +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Education SciencesThis study examines the impact of a Science–Technology–Society–Environment (STSE) educational intervention on the teaching of acid–base reactions to 11th-grade students (n = 17).
Gonçalo Gorito, Carla Morais
doaj +1 more source
E-Journal of Chemistry, 2010 Spectral, cyclic voltammetric and molecular modeling studies have been carried out on some 3-(2-hydroxybenzalhydrazino-4-thiozolyl)coumarins (1), to understand their solution and electrochemical characteristics.
N. Raju, A. Ramachandraiah
doaj +1 more source
The Importance of Acid-Base Equilibria in Bicarbonate Electrolytes for CO2 Electrochemical Reduction and CO Reoxidation Studied on Au(hkl) Electrodes. [PDF]
Langmuir, 2021 Marcandalli G, Villalba M, Koper MTM.
europepmc +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Inhibitory activity of quercetin, its metabolite, and standard antiviral drugs towards enzymes essential for SARS-CoV-2: the role of acid-base equilibria. [PDF]
RSC Adv, 2021 Milanović ŽB +8 more
europepmc +1 more source