Results 91 to 100 of about 9,107,387 (291)
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease
FEBS Letters, EarlyView.Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim +4 more
wiley +1 more source
Nutrition and acid-base balance [PDF]
, 2019 Namen diplomske naloge je bil preučiti kislinsko-bazično ravnovesje telesnih tekočin in njihov vpliv na zdravje. Obravnavali smo uporabnost PRAL vrednosti v prehrani in zdravstvu ter korelacijo med kislinsko-bazičnim ravnovesjem in bolezenskimi stanji ...
Cappellini, Linda
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Impact of the diet on net endogenous acid production and acid–base balance
, 2012 International audienceNet acid production, which is composed of volatile acids (15,000 mEq/day) and metabolic acids (70-100 mEq/day) is relatively small compared to whole-body H+ turnover (150,000 mEq/day).
Chesneau, Caroline +4 more
core +1 more source
Effect of Intravenous Fluid Administration on Acid-Base Balance in Patients Undergoing Colonoscopy
Siriraj Medical Journal, 2014 Objective: Common intravenous (IV) fluids to correct dehydration and acid-base derangement following bowel preparation are 0.9% Saline solution (SS), Lactate Ringer’s solution (LRS) and Acetate Ringer’s solution (ARS).
Phongthara Vichitvejpaisal
doaj
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Pharmacotherapy of Acid-Base disturbances
, 2022 Acid-base balance is a complex and delicate system regulated by multiple components that have a critical function in the human body. The balance of acid and bases is a key component in keeping the homeostasis of blood plasma.
Heimisdóttir, Arndís
core
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Fluid, electrolyte, and acid-base disorders in small animal practice /
, 2006 This comprehensive resource brings together cutting edge information about fluid, electrolyte, and acid-base physiology and fluid therapy as they apply to small animal practice. It also offers complete coverage of relevant physiology and pathophysiology,
DiBartola, Stephen P. +1 more
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