Results 101 to 110 of about 9,107,387 (291)

Chronic impact of topiramate on acid-base balance and potassium in childhood

, 2010
Topiramate, which is commonly prescribed for seizure disorders and migraine prophylaxis, sometimes causes metabolic acidosis and hypokalemia. Since the effects of topiramate on acid-base balance and potassium levels have not been well explored in ...
Bianchetti, Mario G, Simonetti, Giacomo D, Simonetti, Giacomo D., Ramelli, Gian P, Ragazzi, Monica, Belotti, Eva A., Bianchetti, Mario G., Belotti, Eva A, Ramelli, Gian P., Taddeo, Ilaria, Pifferini, Rosanna, Bianchetti, Mario Giovanni, Ramelli GP, Simonetti GD, Taddeo I, Simonetti, Giacomo, Ragazzi M, Bianchetti MG, Pifferini R, Belotti EA, Gian P. Ramelli, Rosanna Pifferini, Mario G. Bianchetti, Monica Ragazzi, Eva A. Belotti, Giacomo D. Simonetti, Ilaria Taddeo   +26 more
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

STUDIES ON ACID-BASE BALANCE IN MAINTENANCE HEMODIALYSIS PART1. CHANGES OF ACID-BASE BALANCE IN THE COURSE OF HEMODIALYSIS [PDF]

, 1972
Acid-base balance was studied before, during and after hemodialysis on four patients on the maintenance hemodialysis with the Kiil type artificial kidney.
田戸, 治
core  

Nutritional Strategies for Mitigating Heat Stress in Broilers: A Review of Acid-base Balance and Osmoregulation

International Journal of Bio-Resource and Stress Management
This review focused on the mechanisms of action and effects of these dietary additives in maintaining acid-base balance and osmoregulation under heat stress conditions.
Eliza Thote, Birjesh Yeltiwar, Sunil Kumar Meena, Samiksha Suroshe, Ajay Mendake   +4 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Animal nutrition and acid-base balance.

, 2001
In domestic animals, acid-base balance may be influenced by nutrition. The major research effort in this area has been made on the prevention of hypocalcemic postparturient paresis in dairy cows.
Riond JL, Jean-Luc Riond
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Short-term regulation of acid-base homeostasis

, 2007
The first in this two-part article explores the short-term homeostatic mechanisms involved in maintaining the ‘acid-base balance’ of body fluids. The second article identifies the intermediate and long-term homeostatic mechanisms involved in maintaining ...
McVicar, Andrew, Clancy, John
core   +1 more source

The kidney and the balance of sulfur and nitrogen as fundamental components of pH homeostasis

Physiological Reports
The homeostasis of blood and tissue pH is fundamental for life, and pH imbalances may lead to coma and death. The regulation of the acid–base balance involves primarily the lungs and kidneys, and is strictly integrated via the endocrine and nervous ...
Vincenzo Graziano, Antonio Angeloni, Paolo Mené, Andrea Bellelli   +3 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source