Results 31 to 40 of about 431,167 (287)

Regulation of metabolism by miR-378 [PDF]

open access: yes, 2014
The present invention provides a method of regulating fatty acid metabolism in a cell by contacting the cell with a modulator of miR-378 and/or miR-378* activity or expression.
Carrer, Michele, Olson, Eric N.
core   +1 more source

Fast-acting antacids and scope of application in the current treatment of acid-base disorders

open access: yesМедицинский совет, 2014
Acid-base disorders today represent a serious problem not only for the population in general, but for every single patient. The term acid-base disorders is used to denote pathological conditions resulting from aggressive action of hydrochloric acid on ...
I. N. Nikushina   +2 more
doaj   +1 more source

Automatic real-time analysis and interpretation of arterial blood gas sample for Point-of-care testing: Clinical validation.

open access: yesPLoS ONE, 2021
BackgroundPoint-of-care arterial blood gas (ABG) is a blood measurement test and a useful diagnostic tool that assists with treatment and therefore improves clinical outcomes. However, numerically reported test results make rapid interpretation difficult
Sancho Rodríguez-Villar   +17 more
doaj   +1 more source

A Randomized, Controlled, Phase 2 Study of Maralixibat in the Treatment of Itching Associated With Primary Biliary Cholangitis. [PDF]

open access: yes, 2019
Primary biliary cholangitis (PBC) is typically associated with elevated serum bile acid levels and pruritus, but pruritus is often refractory to treatment with existing therapies.
Apostol, George   +15 more
core   +2 more sources

Alcohol consumption and leukocyte telomere length. [PDF]

open access: yes, 2019
The relationship between alcohol consumption and mortality generally exhibits a U-shaped curve. The longevity observed with moderate alcohol consumption may be explained by other confounding factors, and, if such a relationship is present, the mechanism ...
Dixit, Shalini   +9 more
core   +2 more sources

Co-Catalytic Metallopeptidases as Pharmaceutical Targets [PDF]

open access: yes, 2003
Understanding the reaction mechanism of co-catalytic metallopeptidases provides a starting point for the design and synthesis of new molecules that can be screened as potential pharmaceuticals. Many of the enzymes that contain co-catalytic metallo-active
Bzymek, Krzysztof P.   +2 more
core   +2 more sources

Stewart’s Approach for Acid-base Disorders: Does the Strong Ion Difference and Effects Have an Impact on Intensive Care Unit Mortality?

open access: yesTürk Yoğun Bakim Derneği Dergisi, 2023
Objective:The diagnosis and treatment of electrolyte and acid-base imbalances in intensive care unit (ICU) patients have critical importance. The value of Stewart’s approach in revealing acid-base disorders is known.
Furkan Tontu   +5 more
doaj   +1 more source

The role of modern antacid therapy in acid-base disorders

open access: yesМедицинский совет, 2014
Acid-base disorders (ABD) today pose a serious healthcare and social problem. With a profound negative impact on the quality of life of patients, they are potentially dangerous in provoking life-threatening conditions; to different extents, ABD affects ...
AN Kazyulin, EB Grischenko
doaj   +1 more source

A brief history of research on the genetics of alcohol and other drug use disorders. [PDF]

open access: yes, 2014
ObjectiveThis article reviews developments in research on genetic influences on alcohol and other drug use and disorders over the past 7 decades.MethodThe author began with a review of the flow and content of articles published in the three iterations of
Schuckit, Marc A
core   +2 more sources

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