Results 21 to 30 of about 8,315 (260)

Potentiometric investigation of acid-base equilibria of two new pyrimidine derivatives in various methanol-water media [PDF]

Journal of the Serbian Chemical Society, 2006
The acid-base properties of 1-amino-5-benzoyl-4-phenyl-1H-pyrimidine-2-one (L1) and 1-amino-5-benzoyl-4-phenyl-1H-pyrimidine-2-thione (L2) were investigated potentiometrically at an ionic strength of 0.10M(LiCl) in 19.8, 33.6 and 55.9 % (v/v) methanol ...
Kiliç Hasan, Birol Er
doaj   +1 more source

Acid-Base Equilibrium and Dielectric Environment Regulate Charge in Supramolecular Nanofibers

Frontiers in Chemistry, 2022
Peptide amphiphiles are a class of molecules that can self-assemble into a variety of supramolecular structures, including high-aspect-ratio nanofibers.
Rikkert J. Nap, Rikkert J. Nap, Baofu Qiao, Liam C. Palmer, Liam C. Palmer, Samuel I. Stupp, Samuel I. Stupp, Samuel I. Stupp, Samuel I. Stupp, Samuel I. Stupp, Monica Olvera de la Cruz, Monica Olvera de la Cruz, Monica Olvera de la Cruz, Monica Olvera de la Cruz, Monica Olvera de la Cruz, Igal Szleifer, Igal Szleifer, Igal Szleifer   +17 more
doaj   +1 more source

Computer Simulations of Static and Dynamical Properties of Weak Polyelectrolyte Nanogels in Salty Solutions

Gels, 2017
We investigate the chemical equilibria of weak polyelectrolyte nanogels with reaction ensemble Monte Carlo simulations. With this method, the chemical identity of the nanogel monomers can change between neutral or charged following the acid-base ...
David Sean, Jonas Landsgesell, Christian Holm   +2 more
doaj   +1 more source

Computational investigation on the antioxidant activities and on the Mpro SARS-CoV-2 non-covalent inhibition of isorhamnetin

Frontiers in Chemistry, 2023
In the present work, we report a computational study on some important chemical properties of the flavonoid isorhamnetin, used in traditional medicine in many countries.
Maciej Spiegel, Maciej Spiegel, Giada Ciardullo, Tiziana Marino, Nino Russo   +4 more
doaj   +1 more source

Kolbe Electrolysis for the Conversion of Carboxylic Acids to Valuable Products—A Process Design Study

Clean Technologies, 2021
The substitution of fossil resources by renewable alternatives is a major challenge for our society. Kolbe electrolysis converts carboxylic acids to hydrocarbons, which can be used as base chemicals, specialty chemicals, or fuels. Carboxylic acids may be
Daniel Klüh, Wolfgang Waldmüller, Matthias Gaderer   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The Difference of the Complex Formation of the Samarium (3+) Ion with the L-malic Acid as Compared to the Neodymium (3+) Ion

Eurasian Chemico-Technological Journal, 2004
The complex formation of the neodymium Nd3+ ion and the samarium Sm3+ ion with L-malic acid (H3Mal) in the aqueous solutions was studied by pH-metric titration in pH region 2.80 to 10.00 and constant ionic strength 0.1 M KCl at 25 °C.
Vladimir Yu. Buzko, Igor V. Sukhno, Margarita B. Gavriluyk, Victor T. Panyushkin   +3 more
doaj   +1 more source

3D Interaction Homology: Computational Titration of Aspartic Acid, Glutamic Acid and Histidine Can Create pH-Tunable Hydropathic Environment Maps

Frontiers in Molecular Biosciences, 2021
Aspartic acid, glutamic acid and histidine are ionizable residues occupying various protein environments and perform many different functions in structures. Their roles are tied to their acid/base equilibria, solvent exposure, and backbone conformations.
Noah B. Herrington, Glen E. Kellogg, Glen E. Kellogg   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source