Results 61 to 70 of about 59,532 (299)

Functionalisation of colloidal transition metal sulphides nanocrystals: A fascinating and challenging playground for the chemist [PDF]

open access: yes, 2017
Metal sulphides, and in particular transition metal sulphide colloids, are a broad, versatile and exciting class of inorganic compounds which deserve growing interest and attention ascribable to the functional properties that many of them display.
Dengo, Nicola   +2 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Tautomeric Equilibria Studies by Mass Spectrometry [PDF]

open access: yes, 2008
Tautomerism in organic chemistry has been extensively studied in condensed phase by spectrometric methods, mainly by IR and NMR techniques. Mass spectrometry studies start 40 years ago but just recently it has been recognized the importance of the mass ...
Eduardo A. Castro   +3 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

On the mechanism of photocatalytic reactions with eosin Y

open access: yesBeilstein Journal of Organic Chemistry, 2014
A combined spectroscopic, synthetic, and apparative study has allowed a more detailed mechanistic rationalization of several recently reported eosin Y-catalyzed aromatic substitutions at arenediazonium salts.
Michal Majek   +2 more
doaj   +1 more source

Challenges for the development of a biotic ligand model predicting copper toxicity in estuaries and seas [PDF]

open access: yes, 2012
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2011 SETAC.An effort is ongoing to develop a biotic ligand model (BLM) that predicts copper (Cu) toxicity in estuarine and marine ...
de Polo, A, Scrimshaw, MD
core   +1 more source

The C Terminus of the Ribosomal-Associated Protein LrtA Is an Intrinsically Disordered Oligomer [PDF]

open access: yes, 2018
The 191-residue-long LrtA protein of Synechocystis sp. PCC 6803 is involved in post-stress survival and in stabilizing 70S ribosomal particles. It belongs to the hibernating promoting factor (HPF) family, intervening in protein synthesis.
Arbe Méndez, María Aranzazu   +4 more
core   +5 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Solvent Effects on Acid-Base Equilibria

open access: yes, 1972
Department of Chemistry, Indian Institute of Technology, Madras-36 Received 12 October 1971 Equilibrium constants for acidlbase equilibria of the type RC6H4NH3+ + C6H3NH2 = C6H3NH3+ + RC6H4NH2 have been determined by an indicator method in a few solvents and the effect of solvent on such equilibria is discussed.
C. KALIDAS   +2 more
openaire   +1 more source

Conditions and reactions defining dye bacteriostasis [PDF]

open access: yes, 1926
The continued study of bacterial cells from the point of view which assumes that they behave as conjugated proteins (Stearn and Stearn, 1924a and b) has led to an intensive study of the action of both basic and acid dyes in their bacteriostatic and ...
Stearn, Allen E., Stearn, Esther Wagner
core  

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