Results 41 to 50 of about 113,055 (306)

Fluorescence and photostability studies of anthracene-9-carboxylic acid in different media

International Journal of Photoenergy, 2000
Electronic absorption and fluorescence spectra of anthracene-9-carboxylic acid (ANCA) were studied in different homogeneous solvents, binary protic/aprotic solvent mixtures and in heterogeneous solutions of the cationic cetyltrimethyl ammonium bromide ...
M. S. A. Abdel-Mottaleb, H. R. Galal, A. F. M. Dessouky, M. El-Naggar, D. Mekkawi, S. S. Ali, G. M. Attya   +6 more
doaj   +1 more source

Serum markers and development of delayed neuropsychological sequelae after acute carbon monoxide poisoning: anion gap, lactate, osmolarity, S100B protein, and interleukin-6 [PDF]

Clinical and Experimental Emergency Medicine, 2018
Objective Reliable biomarkers of delayed neuropsychological sequelae (DNS) after acute carbon monoxide (CO) poisoning are lacking. This study investigated the associations between potential serum markers and the development of DNS after acute CO ...
Hyukhoon Kim, Sangchun Choi, Eunjung Park, Eunhui Yoon, Younggi Min, Samsun Lampotang   +5 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Участие на калций и магнезий в киселинно-алкалното равновесие в Канелени горски почви

Почвознание, агрохимия и екология, 2010
Soils of South Bulgaria (Luvisols and Planosols, WRBSR, 2006) are known as rather different regarding nature оr quantity of their clay minerals. In this article, аn attempt to find out а general equation for the dependence between pH of soil and the ...
МАРИЯ ТАНЕВА, РОСИЦА ТОНЧЕВА, НАТАЛИЯ ЖИВКОВА   +2 more
doaj  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

A detailed UV–Vis spectral investigation of six azo dyes derived from benzoic- and cinnamic acids: experimental and theoretical insight

Comptes Rendus. Chimie, 2021
Six donor–${\pi }$–acceptor azo dyes, with altered donor- (p-hydroxyphenyl- and naphthalene-2-ol) and carboxylic based acceptor groups, were subjected to detailed solvatochromic and tautomeric investigation in different environments by experimental and ...
Matović, Luka, Lađarević, Jelena, Vitnik, Željko, Vitnik, Vesna, Mijin, Dušan   +4 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

The effect of NaCl 0.9% and NaCl 0.45% on sodium, chloride, and acid‐base balance in a PICU population

Jornal de Pediatria (Versão em Português), 2015
Objectives: To study the effect of two intravenous maintenance fluids on plasma sodium (Na), and acid‐base balance in pediatric intensive care patients during the first 24 h of hospitalization.
Helena Isabel Almeida, Maria Inês Mascarenhas, Helena Cristina Loureiro, Clara S. Abadesso, Pedro S. Nunes, Marta S. Moniz, Maria Céu Machado   +6 more
doaj   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source