Results 31 to 40 of about 59,884 (251)

The Domino Effect: Hyperventilation, Hypocapnia, and Tetany in Airway Management [PDF]

Journal of Clinical and Diagnostic Research
Airway management represents one of the most critical challenges in anaesthesiology, particularly in patients with history of head and neck surgeries due to altered anatomy.
Subha Teresa Jose Vazhakalayil, Sandeep Veer, Brinda Badam, Jayant Mane   +3 more
doaj   +1 more source

Cholecystectomy promotes the development of colorectal cancer by the alternation of bile acid metabolism and the gut microbiota

Frontiers in Medicine, 2022
The incidence and mortality of colorectal cancer (CRC) have been markedly increasing worldwide, causing a tremendous burden to the healthcare system. Therefore, it is crucial to investigate the risk factors and pathogenesis of CRC.
Xi Jiang, Zhongxiu Jiang, Qi Cheng, Wei Sun, Min Jiang, Yan Sun   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Study on the content of nurses' right to prescribe medicines for correcting water, electrolytes, acid⁃base disorders, blood volume expansion medicines and nutrition medicines

Huli yanjiu, 2020
ObjectiveTo probe into the contents and forms of prescription right of drugs that correcting imbalance of water,electrolyte and acid⁃base,dilatating blood volume and providing nutrition,and prescirbed by general surgical nurses who met applicant ...
JIA Xiaoyue, HAN Shifan, ZHU Ruifang, CAO Yan, MENG Yifei, XU Zhuya, WANG Yaping   +6 more
doaj  

Hyperchloremic metabolic acidosis during bipolar transurethral resection of the prostate: a report of two cases

Journal of International Medical Research, 2021
Compared with monopolar transurethral resection of the prostate (TURP), which requires electrolyte-free irrigation fluid, normal saline can be used as the irrigation solution in bipolar and laser TURP.
Ann Hee You, Ji Yoo Lee, Jeong-Hyun Choi, Mi Kyeong Kim   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Correlation of base deficit and age shock index with in-hospital mortality in geriatric major trauma patients: a 1-year retrospective study at a single level I trauma center in Indonesia [PDF]

Journal of Trauma and Injury
Purpose Base deficit (BD) and age shock index have been utilized as an indicator of resuscitation adequacy and a predictor of poor outcomes in trauma cases, respectively.
Miftahul Khairat Musmar Elbama, M. Iqbal Rivai, Irwan, Avit Suchitra, Aulia Rahman, Rose Dinda Martini   +5 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source