Results 51 to 60 of about 3,624,683 (287)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Probable changes in lake chemistry in Canada’s Atlantic Provinces under proposed North American emission reductions [PDF]
Hydrology and Earth System Sciences, 2003 Atlantic Canada, located in the extreme north-eastern portion of North America, receives acid precipitation from all major acid emission sources on the eastern part of the continent. The region was glaciated and has thin soils over a generally poorly
T. A. Clair, I. F. Dennis, B. J. Cosby
doaj
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
National Atmospheric Deposition Program 2014 Annual Summary [PDF]
, 2015 The National Atmospheric Deposition Program (NADP) provides fundamental measurements that support informed decisions on environmental issues related to precipitation and atmospheric deposition chemistry, as well as atmospheric mercury and ammonia.
core
Hexanoic Acid-Induced Resistance Against Botrytis cinerea in Tomato Plants
Molecular Plant-Microbe Interactions, 2009 We have demonstrated that root treatment with hexanoic acid protects tomato plants against Botrytis cinerea. Hexanoic acid-induced resistance (Hx-IR) was blocked in the jasmonic acid (JA)-insensitive mutant jai1 (a coi1 homolog) and in the abscisic acid (
Begonya Vicedo +7 more
doaj +1 more source
Environmental Microbiome, 2022 Background The nitrogenous compound deposited from the atmosphere to the soil is complex, but most field experiments mimic nitrogen deposition with the acid NH4NO3 alone.
Tingting Li +6 more
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Acid deposition at Rothamsted, Saxmundham and Woburn, 1969–83
, 1985 Rainfall has become less acid at Rothamsted and Saxmundham over the period 1969–83. The pH of rain at these two sites has increased from 4.4–4.6 to about 4.8–4.9; at Woburn it has remained approximately constant at 4.4–4.6.
P. R. Poulton +3 more
core +1 more source
An integrated study of CaCO3 formation and inhibition [PDF]
, 2008 The management of mineral scale is a challenge in many industrial fields and environmental issues relating to eutrophication are leading industry to develop environmentally-friendly solutions to scale control.
Martinod, Aurelie Charlotte
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FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source