Results 51 to 60 of about 472,598 (296)

Effects of short-term simulated acid rain and nitrogen deposition on soil nutrients and enzyme activities in Cunninghamia lanceolata plantation

Frontiers in Ecology and Evolution
Acid rain and nitrogen deposition are emerging as global scale environmental issues due to increasing industrial emissions and agricultural pollutants, which seriously impac t the sustainable development of global ecosystems.
Yong Ding, Lianhao Sun, Chong Li, Chong Li, Meiling Chen, Yuexiang Zhou, Miaojing Meng, Zhenghao Li, Jinchi Zhang, Xin Liu   +9 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Evaluation of streamwater composition changes in the Vosges Mountains (NE France): 1955–2005 [PDF]

, 2009
n 1995, in the southwestern Vosges Mountains (NE France), 158 of 395 streams (40%) had a pH lower than 5.5 at baseflow. As elsewhere in Europe, acid deposition has decreased since the seventies, as has base cation deposition.
Boudot, J.P., Party, J.P., Pollier, Benoit, Tixier, Guillaume, Nedeltcheva, Théodora, Party, Jean-Paul, Dambrine, Etienne, Dambrine, Etienne, E., Angéli, Nicolas, Guerold, F., Tixier, G., Guérold, François, Boudot, Jean-Pierre, Probst, Anne, Bourrié, Guilhem   +14 more
core   +1 more source

Hexanoic Acid-Induced Resistance Against Botrytis cinerea in Tomato Plants

Molecular Plant-Microbe Interactions, 2009
We have demonstrated that root treatment with hexanoic acid protects tomato plants against Botrytis cinerea. Hexanoic acid-induced resistance (Hx-IR) was blocked in the jasmonic acid (JA)-insensitive mutant jai1 (a coi1 homolog) and in the abscisic acid (
Begonya Vicedo, Víctor Flors, María de la O Leyva, Ivan Finiti, Zhana Kravchuk, María Dolores Real, Pilar García-Agustín, Carmen González-Bosch   +7 more
doaj   +1 more source

Nitrogen deposition experiment mimicked with NH4NO3 overestimates the effect on soil microbial community composition and functional potential in the Eurasian steppe

Environmental Microbiome, 2022
Background The nitrogenous compound deposited from the atmosphere to the soil is complex, but most field experiments mimic nitrogen deposition with the acid NH4NO3 alone.
Tingting Li, Zijia Zhang, Yiping Ma, Yuqian Song, Guojiao Yang, Xingguo Han, Ximei Zhang   +6 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Groundwater Al dynamics in boreal hillslopes at three integrated monitoring sites along a sulphur deposition gradient in Sweden [PDF]

, 2010
Data from 4 soil water and groundwater transects from 3 small, boreal catchments situated along a south-north sulphur deposition gradient in Sweden were studied to assess whether the soils in the near stream zone can significantly modify the groundwater ...
Cory, Neil, Löfgren, Stefan
core  

Impacts of nitrogen deposition on vascular plants in Britain: an analysis of two national observation networks [PDF]

, 2011
Large areas of Great Britain currently have nitrogen (N) deposition at rates which exceed the thresholds above which there is risk of damage to sensitive components of the ecosystem (critical loads).
C. D. Preston, Walker, K.J., Henrys, P.A., Rowe, E. C., Emmett, B. A., S. M. Smart, Henrys, P. A., Maskell, L. C., Emmett, B.A., Rowe, E.C., L. C. Maskell, Preston, C.D., K. J. Walker, C. J. Stevens, Stevens, C.J., Smart, S.M., Preston, C. D., Gowing, D.J., Smart, S. M., P. A. Henrys, Stevens, C. J., E. C. Rowe, D. J. Gowing, A. Crowe, Maskell, L.C., Crowe, A., Walker, K. J., B. A. Emmett, Gowing, D. J.   +28 more
core   +1 more source