Results 71 to 80 of about 4,277,838 (300)
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
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Dissociation Constants of Diethyldithiocarbamic Acid
, 1966 Dienthyldithiocarbamic acid was previously reported to be a dibasic one with pKD1=7.5 and pKD2= 8.4 (where pKp terms represent the negative logarithm of the dissociation constants). These values cannot be considered acceptable. The more correct values of pKD1 and pKD2 obtained by the method of successive approximations, correction term method as well ...
K. P. Soni, A. M Trivedi, I M. Bhatt
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, 1975 Shri G. S. Institute of Technology and Science, Indore Manuscript received 18 December 1973; revised 12 November 1974; accepted 11 December 1974 The acid dissociation constant of streptomycin perchlorate and the stability constant of its Cu(II) complex
R. VIJAYVARGIYA, J. K. AGRAWAL
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FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
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FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
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Adenosine triphosphate as a modulator of protein interactions and stability
FEBS Open Bio, EarlyView.ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
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LIX.—The dissociation constant of azoimide (hydrazoic acid) [PDF]
J. Chem. Soc., Trans., 1900 n ...
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, 1945 The ionization of an acid in water may be represented by the following equilibrium; HA + H₂O ⇌ H₃O⁺ + A’ and by applying the law of mass action the activity of the water being assumed constant it can be shown that [equation here] where Kₐ
Jones, A. V.
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Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
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Journal of Chemistry, 2013 The proton-ligand dissociation constant of 4-(4-amino-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-ylideneamino)-phenol () and 4-(4-amino-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-ylideneamino)-benzoic acid () and metal-ligand stability constants of ...
A. A. El-Bindary +3 more
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