Results 101 to 110 of about 541,119 (315)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

The status of phosphorus of a calcareous flush at Bakethin Reservoir, Northumberland [PDF]

, 1993
In order to assess the status of phosphorus of a calcareous flush at Bakethin reservoir, Northumberland, chemical analyses of the concentration of phosphorus in the water and the phosphatase activity of cyanobacteria, Nostoc and Rivularia, as well as the
Bresnan, Eileen
core  

Receptor-specific regulation of phosphatidylinositol 3'-kinase activation by the protein tyrosine phosphatase Shp2

, 2002
Receptor tyrosine kinases (RTKs) play distinct roles in multiple biological systems. Many RTKs transmit similar signals, raising questions about how specificity is achieved.
Zhang, S., Wen, G., Minichiello, L., Zhang, Si Qing, Wen, Gengyun, Araki, T., Klein, R., Tsiaras, B., Neel, Benjamin G, Neel, B., Araki, Toshiyuki, Klein, Ruediger, Minichiello, Liliana, Tsiaras, William G   +13 more
core   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Phosphate Uptake from Phytate Due to Hyphae-Mediated Phytase Activity by Arbuscular Mycorrhizal Maize

Frontiers in Plant Science, 2017
Phytate is the most abundant form of soil organic phosphorus (P). Increased P nutrition of arbuscular mycorrhizal plants derived from phytate has been repeatedly reported.
Gu Feng, Xin-Xin Wang, Xin-Xin Wang, Ellis Hoffland, Thomas W. Kuyper   +4 more
doaj   +1 more source

An ecophysiological study on the moss hydrogoniuh fontanum from the Asir mountains, Saudi Arabia [PDF]

, 1992
The thesis describes a study on the ecophysiology of the moss Hydrogonium fontanum (C. Mail.) Jaeg., the dominant plant at a waterfall in Saudi Arabia.
Al-Shehri, Abdulrahman M., Al-Shehri, A.M   +1 more
core  

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Phosphorus dynamics in the swale - Ouse River system [PDF]

, 1998
A study was made of the phosphorus ecology of the Swale - Ouse river in northern England. It ranges from a stream draining a peat moorland to a mature river influenced by urbanisation (estimated population 250 000) and intensive agriculture.
Christmas, Martin, Christmas, M.
core  

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

ACID PHOSPHATASE ACTIVITY IN MELANOSOMES OF MELANOCYTES

, 1968
A combined cytochemical and electron microscopic demonstration of acid phosphatase activity of melanosomes in melanocytes was carried out on B-16 and Harding-Passey mouse melanoma and the retinal pigment epithelium of white leghorn chick embryos.

core   +1 more source