Results 81 to 90 of about 3,329,624 (262)

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Acid Phosphatase and Protease Activities in Immobilized Rat Skeletal Muscles

open access: yes, 1982
The effect of hind-limb immobilization on selected lysosomal enzyme activities was studied in rat hind-limb muscles composed primarily of type I, IIA, or IIB fibers. Following immobilization, acid protease and acid phosphatase both exhibited significant (
Frank A. Witzmann   +5 more
core   +1 more source

Enzymatic and Immunological Studies of Prostatic Acid Phosphatase [PDF]

open access: yes, 1979
Levels of serum acid phosphatase are elevated in prostatic cancer patients as compared with those of normal human. Prostatic cancer patients with bone metastasis show about 2 to 5 fold increased activities of serum acid phosphatase while patients without
Nakano, Shingo   +4 more
core   +2 more sources

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

The membrane bound phosphatidic add phosphatase from avocado [PDF]

open access: yes, 1997
Phosphatidate Phosphatase (EC 3.1.3.4) is an important enzyme in plant lipid metabolism as it lies at a theoretical branchpoint between phospholipid and triacylglycerol biosyntheses.
Pearce, Matthew L., Pearce, M.L.
core  

Ascorbic acid and alkaline phosphatase activity

open access: yes, 1983
Ascorbic acid is found strikingly to decrease the activity of bovine kidney alkaline phosphatase in vitro. The inhibition of alkaline phosphatase is a function of ascorbic acid concentration and is time and temperature dependent.
Castelli, A.   +9 more
core   +1 more source

Determination of Embryotoxic Effects of In Ovo Administered Propofol on Peripheral Blood Alpha Naphthyl Acetate Esterase and Acid Phosphatase-Positive Lymphocytes

open access: yes, 2023
Objective: The aim of this study is to determine the possible embryotoxic effects of propofol, a general anaesthetic agent that is commonly used in clinical practice, on peripheral blood lymphocytes using enzyme histochemical techniques.
Yasemin Öznurlu   +10 more
core   +1 more source

Actividad de las fosfatasas ácidas y alcalinas (extracelulares e intracelulares) en hongos de la rizosfera de Arachis hypogaea (Papiloneaceae)

open access: yesRevista de Biología Tropical, 2004
El papel potencial de los hongos aislados de la rizosfera del maní, en la producción de fosfatasas ácidas y alcalinas extracelulares e intracelulares, fue evaluado in vitro. Las fosfatasas ácidas y alcalinas extracelulares, mostraron la mayor actividad y
Y. Gómez-Guiñán
doaj  

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

open access: yesMolecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna   +8 more
wiley   +1 more source

Water chemistry and algal phosphatase activity in zinc-contaminated streams [PDF]

open access: yes, 1990
A study was carried out on algal phosphatase activity and water chemistry in zinc-contaminated streams in the Northern Pennine Orefield. Fourteen field sites were studied; They ranged from low contaminated to high-zinc sites (0.1 mg 1(^-1) to 19.4 mg 1(^-
Bellos, D.
core  

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