Results 91 to 100 of about 783,120 (310)

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

open access: yesFEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

New insights into the anti-inflammatory mechanisms of glucocorticoids : an emerging role for glucocorticoid-receptor-mediated transactivation [PDF]

open access: yes, 2013
Glucocorticoids are anti-inflammatory drugs that are widely used for the treatment of numerous (autoimmune) inflammatory diseases. They exert their actions by binding to the glucocorticoid receptor (GR), a member of the nuclear receptor family of ...
Dejager, Lien   +3 more
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Actividad de las fosfatasas ácidas y alcalinas (extracelulares e intracelulares) en hongos de la rizosfera de Arachis hypogaea (Papiloneaceae)

open access: yesRevista de Biología Tropical, 2004
El papel potencial de los hongos aislados de la rizosfera del maní, en la producción de fosfatasas ácidas y alcalinas extracelulares e intracelulares, fue evaluado in vitro. Las fosfatasas ácidas y alcalinas extracelulares, mostraron la mayor actividad y
Y. Gómez-Guiñán
doaj  

Distribution of Phosphate Solubilizing Bacteria and Soil Phosphatase Activity in Different Land Uses

open access: yesمجله آب و خاک, 2016
Introduction: Phosphorous is one of the essential macronutrients for plant growth and development but its mobility in soil is very low. The utilization of the soil biological potential, in particular phosphate solubilizing bacteria, is an efficient way ...
M. R. Sarikhani   +2 more
doaj   +1 more source

Immune myopathies with perimysial pathology: Clinical and laboratory features [PDF]

open access: yes, 2018
ObjectiveImmune myopathies with perimysial pathology (IMPP) have a combination of damage to perimysial connective tissue and muscle fiber necrosis, more prominent near the perimysium.
Bucelli, Robert C, Pestronk, Alan
core   +2 more sources

A 73‐Year‐Old Man With Several Years of Difficulty Climbing Stairs and Frequent Tripping

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 73‐year‐old man presented with progressive weakness and atrophy predominantly affecting the distal finger flexors and quadriceps muscles. Electrophysiological studies demonstrated mixed myogenic and neurogenic features. Muscle MRI showed inflammatory changes, and muscle biopsy revealed granulomatous myositis with histologic features ...
Mehmet Can Sari   +3 more
wiley   +1 more source

The effect of endodontic filling agents on the activity of the regeneration processes of bone tissue in the experiment

open access: yesJournal of Medical Science, 2018
Introduction. Highly important is to regenerate the inflammatory destructive processes of bone tissue outside the apical area of the tooth that would optimize reparative bone formation, mineralization of tooth tissues, restoration of periodontal function
Iryna Han   +2 more
doaj   +1 more source

Cluster Analysis of Ranunculus Species [PDF]

open access: yes, 2002
The aim of the experiment was to examine whether the morphological characters of eleven species of Ranunculus collected from a number of populations were in agreement with the genetic data (isozyme).
SURANTO,
core   +2 more sources

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

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