Results 51 to 60 of about 796,985 (357)

Immunogenic Modulations Induced by Prospective Anti-Malarial Herbal Extracts in Murine Model [PDF]

open access: yes, 2010
Keeping in view the ever increasing problem of drug resistance and affordability of the antimalarial drugs by the poor mass, herbal medicines can become an important and alternative sustainable strategy for malaria treatment.
Chinmoy Karjee   +11 more
core   +1 more source

Importance of geometry of the extracellular matrix in endochondral bone differentiation. [PDF]

open access: yes, 1984
Subcutaneous implantation of coarse powders (74-420 micron) of demineralized diaphyseal bone matrix resulted in the local differentiation of endochondral bone.
Reddi, AH, Sampath, TK
core   +1 more source

Localized inhibition of protein phosphatase 1 by NUAK1 promotes spliceosome activity and reveals a MYC-sensitive feedback control of transcription. [PDF]

open access: yes, 2020
Deregulated expression of MYC induces a dependence on the NUAK1 kinase, but the molecular mechanisms underlying this dependence have not been fully clarified.
Ade, C.P.   +18 more
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Aluminium induced acid phosphatase activity in roots of Al-sensitive and Al-tolerant barley varieties

open access: yesPlant, Soil and Environment, 2002
In barley roots significant increase of acid phosphatase activity was observed during Al treatment. Especially steep increase was found in the roots of Al-sensitive cv.
J. Huttová, L. Tamás, I. Mistrík
doaj   +1 more source

Species- and organ-specificity of secretory proteins derived from human prostate and seminal vesicles [PDF]

open access: yes, 1990
Polyclonal antibodies against semenogelin (SG) isolated from human seminal vesicle secretion and acid phosphatase (PAP), β‐microseminoprotein (β‐MSP), and Prostate‐Specific Antigen (PSA) derived from human prostatic fluid, as well as a monoclonal ...
Abrahamsson, P. ‐A,   +6 more
core   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Phosphatase activity of Poa pratensis seeds. I. Preliminary studies on acid phosphatase II

open access: yesActa Societatis Botanicorum Poloniae, 2015
Acid phosphatase (EC 3.1.3.2) was extracted with 0.1 M sodium acetate buffer pH 5.1 from Poa pratensis seeds, and separated into three fractions by chromatography on DEAE cellulose.
I. Lorenc-Kubis, B. Morawiecka
doaj   +1 more source

Effect of gallic acid on Alkaline phosphatase gene expression in vascular smooth muscle cells [PDF]

open access: yes, 2015
Background and purpose: Vascular calcification is an important factor in pathogenesis of atherosclerosis. Studies have shown that alkaline phosphatase increases vascular calcification.
Farrokhi, E.   +4 more
core  

Expansive evolution of the TREHALOSE-6-PHOSPHATE PHOSPHATASE gene family in Arabidopsis [PDF]

open access: yes, 2012
Trehalose is a nonreducing sugar used as a reserve carbohydrate and stress protectant in a variety of organisms. While higher plants typically do not accumulate high levels of trehalose, they encode large families of putative trehalose biosynthesis genes.
Avonce, Nelson   +10 more
core   +2 more sources

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