Results 51 to 60 of about 779,413 (310)

Effect of gallic acid on Alkaline phosphatase gene expression in vascular smooth muscle cells [PDF]

, 2015
Background and purpose: Vascular calcification is an important factor in pathogenesis of atherosclerosis. Studies have shown that alkaline phosphatase increases vascular calcification.
Farrokhi, E., Ghanavati, T., Ghatreh-Samani, K., Heydarian, E., Nikookar, M.   +4 more
core  

Structural and functional characterization of a cold-adapted stand-alone TPM domain reveals a relationship between dynamics and phosphatase activity [PDF]

, 2018
The TPM domain constitutes a family of recently characterized protein domains that are present in most living organisms. Although some progress has been made in understanding the cellular role of TPM-containing proteins, the relationship between ...
Aran, Martin, Cicero, Daniel Oscar, Ithuralde, Raúl Esteban, Pellizza, Leonardo, Smal, Clara, Turjanski, Adrian   +5 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The mRNA expression and enzymatic activity of three enzymes during embryonic development of the hard tick Haemaphysalis longicornis

Parasites & Vectors, 2019
Background Three main enzymes including cathepsin B, cathepsin D and acid phosphatase are involved in vitellin degradation, which is a major biochemical event of the embryonic development and can provide nutrients and metabolites for tick embryos. In the
Tian-Tian Zhang, Zhao-Xi Qiu, Yuan Li, Wen-Ying Wang, Meng-Meng Li, Pei Guo, Jing-Ze Liu   +6 more
doaj   +1 more source

Immunogenic Modulations Induced by Prospective Anti-Malarial Herbal Extracts in Murine Model [PDF]

, 2010
Keeping in view the ever increasing problem of drug resistance and affordability of the antimalarial drugs by the poor mass, herbal medicines can become an important and alternative sustainable strategy for malaria treatment.
Chinmoy Karjee, Dipankar Singha, Guruprasad Mandal, Manoj Das, Niladri Sekhar Bhunia, Sajal Ray, Sanat Biswas, Shyamal Das Gupta, Sreemayee Sarkar, Sudipta Chakraborty, Suman Mukherjee, Swapna Chhetri   +11 more
core   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

Phosphatase activity of Poa pratensis seeds. I. Preliminary studies on acid phosphatase II

Acta Societatis Botanicorum Poloniae, 2015
Acid phosphatase (EC 3.1.3.2) was extracted with 0.1 M sodium acetate buffer pH 5.1 from Poa pratensis seeds, and separated into three fractions by chromatography on DEAE cellulose.
I. Lorenc-Kubis, B. Morawiecka
doaj   +1 more source

A collagen membrane influences bone turnover marker in vivo after bone augmentation with xenogenic bone

Head & Face Medicine, 2020
Background The aim was to compare early biochemical and histological osseous healing of chronic mandibular defects regenerated with bovine bone substitute with and without collagen membrane in vivo.
Henning Staedt, Michael Dau, Eik Schiegnitz, Daniel G. E. Thiem, Olga Tagadiuc, Victor Palarie, Peter Ottl, Bilal Al-Nawas, Peer W. Kämmerer   +8 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Acid Phosphatase and Zinc Tests Are Effective for Semen Examination and Identification to Prove Intercourse

Folia Medica Indonesiana, 2021
The presence of spermatozoa in vagina is a definite sign of sexual intercourse. However, sometimes microscopic examination does not find spermatozoa or reveals a false negative result.
Ahmad Yudianto, Ariyanto Wibowo, Indah Nuraini, Htet Htet Aung   +3 more
doaj   +1 more source