Results 131 to 140 of about 1,727,497 (306)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Nature of serpentinite interactions with low-concentration sulfuric acid solutions

open access: yesGreen Processing and Synthesis
The nature of serpentinite interaction with low-concentration sulfuric acid solutions is studied. Using IR-Fourier spectroscopy, X-ray, and serpentinite leaching with sulfuric acid solutions containing 10–60% of stoichiometrically required amount (SRA ...
Yeskibayeva Chaizada   +4 more
doaj   +1 more source

Amino Acid Solutions for 177Lu-Oxodotreotide Premedication: A Tolerance Study. [PDF]

open access: yesCancers (Basel), 2022
Courault P   +6 more
europepmc   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

THE REGISTERING SYSTEMS FOR THE RADIATION NONDESTRUCTIVE CONTROL ON THE BASIS OF THE THREE-COMPONENT ORGANIC DYES SOLUTIONS

open access: yesПриборы и методы измерений, 2015
Spectral properties of a number of three-component organic dyes of various classes solutions subjected to radiation by gamma and x-ray radiation are investigated.
V. I. Papechyts
doaj  

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Extraction of Copper from Sulfuric Acid Solutions Based on Pseudo-Liquid Membrane Technology. [PDF]

open access: yesMembranes (Basel), 2023
Kostanyan AE   +3 more
europepmc   +1 more source

Acid solutions [PDF]

open access: yesJournal of the Franklin Institute, 1920
openaire   +1 more source

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