Results 151 to 160 of about 778,771 (262)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Comparative Efficacy and Safety of 0.8-L Versus 2-L Polyethylene Glycol-Ascorbic Acid Solutions in Colonoscopy Preparation: A Prospective, Multicenter, Randomized, Controlled Trial. [PDF]

J Gastroenterol Hepatol
Lee B, Keum B, Hong SN, Kim HG, Im JP, Na SY, Kwak MS, Nam K, Byeon JS.   +8 more
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Exploring pH Dynamics in Amino Acid Solutions Under Low-Temperature Plasma Exposure. [PDF]

Molecules
Villavicencio CJG, Silva BC, Matara A, Ptasinska S.   +3 more
europepmc   +1 more source

Vibrational Spectral Analysis of Natisite (Na₂TiSiO₅) and its Structure Evolution in Water and Sulfuric Acid Solutions. [PDF]

Materials (Basel), 2021
Meng F, Liu Y, Wang L, Chen D, Zhao H, Zhen Y, Chen J, Qi T.   +7 more
europepmc   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gabor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

New sugar-derived compounds as inhibitors of carbon steel against corrosion in acid solutions: experimental analyses and theoretical approaches. [PDF]

RSC Adv
Rbaa M, Barrahi A, Seghiri R, Katin KP, Berdimurodov E, Abuelizz HA, Jama C, Bentiss F, Lakhrissi B, Zarrouk A.   +9 more
europepmc   +1 more source

Direct and continuous generation of pure acetic acid solutions via electrocatalytic carbon monoxide reduction. [PDF]

Proc Natl Acad Sci U S A, 2021
Zhu P, Xia C, Liu CY, Jiang K, Gao G, Zhang X, Xia Y, Lei Y, Alshareef HN, Senftle TP, Wang H.   +10 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Choline chloride and amino acid solutions taste and hydration behavior with experimental thermodynamic properties and COSMO-PC-SAFT calculation. [PDF]

Sci Rep
Morsali MA, Golmohammadi B, Shekaari H.
europepmc   +1 more source