Results 51 to 60 of about 11,139 (183)

Isovaleric Acidemia in Jordan

Cureus
Isovaleric acidemia (IVA) was the first condition to be recognized as an organic acid disorder. It is marked by metabolic ketoacidosis with an unexplained anion gap. This study examines IVA in Jordan, laying the groundwork for future studies. Furthermore, it seeks to enhance the understanding of clinical characteristics and outcomes in affected ...
Megdadi, Noor, Alakil, Mo'men, Ghanmiyin, Lina, Maaita, Omar, Abulannaz, Amjad   +4 more
openaire   +2 more sources

Toward implementation of lactate compared with pH in fetal scalp blood sampling during labor: A clinical comparative single‐center study

Acta Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 11, Page 2343-2350, November 2026.
Lactate and pH in fetal blood samples are moderately correlated (r = −0.53). For the StatStrip® Lactate 2, we propose a lactate cutoff value of ≥5.6 mmol/L based on the most optimal balance between sensitivity (78.1% [60.0–90.7%]) and specificity (79.2% [73.4–84.3%]).
Suzanne J. van Woudenberg, Ivonne Mijnheer, Marcel M. G. J. van Borren, Lian Roovers, Femi Janse   +4 more
wiley   +1 more source

Association between different types and characteristics of fetal deceleration during labour and neonatal acidemia at delivery: A case-control study

European Journal of Obstetrics & Gynecology and Reproductive Biology: X
Objective: Classification of fetal heart rate (FHR) decelerations as suspicious or pathological differs between current interpretation templates for intrapartum cardiotocography.
Maria Fogelberg, Charlotte Dahlbäck, Frida Ekengård, Gisela Rickle, Andreas Herbst   +4 more
doaj   +1 more source

Increased compensatory kidney workload results in cellular damage in a short time porcine model of mixed acidemia - Is acidemia a 'first hit' in acute kidney injury?

PLoS ONE, 2019
Acute kidney injury (AKI) corrupts the outcome of about 50% of all critically ill patients. We investigated the possible contribution of the pathology acidemia on the development of AKI.
Martin Russ, Sascha Ott, Janis R Bedarf, Michael Kirschfink, Bernhard Hiebl, Juliane K Unger   +5 more
doaj   +1 more source

A Machine Learning and Explainable Artificial Intelligence approach for Insurance Fraud Classification

Inteligencia Artificial
This study addresses the critical issue of fraud in the vehicle insurance market by introducing a comprehensive framework that employs advanced detection models, including explainable artificial intelligence (XAI) and heterogeneous classifiers to ...
Diana Olivia, Zaid Khan, Sucharitha Shetty   +2 more
doaj  

Acute Pancreatitis with Rapid Clinical Improvement in a Child with Isovaleric Acidemia

Case Reports in Pediatrics, 2013
Isovaleric acidemia is a rare branched-chain organic acidemia. The authors describe a 3.5-year-old girl with isovaleric acidemia and acute abdominal pain associated with bilious emesis.
Elpis Mantadakis, Ioannis Chrysafis, Emmanouela Tsouvala, Athanassios Evangeliou, Athanassios Chatzimichael   +4 more
doaj   +1 more source

Impaired mitophagy links mitochondrial disease to epithelial stress in methylmalonyl-CoA mutase deficiency

Nature Communications, 2020
Methylmalonic acidemia is an inherited metabolic disease caused by loss or mutation of the enzyme MMUT. Here the authors use cell and animal models to show that MMUT mutations lead to defective mitophagy and stress in kidney cells, contributing to the ...
Alessandro Luciani, Anke Schumann, Marine Berquez, Zhiyong Chen, Daniela Nieri, Mario Failli, Huguette Debaix, Beatrice Paola Festa, Natsuko Tokonami, Andrea Raimondi, Alessio Cremonesi, Diego Carrella, Patrick Forny, Stefan Kölker, Francesca Diomedi Camassei, Francisca Diaz, Carlos T. Moraes, Diego Di Bernardo, Matthias R. Baumgartner, Olivier Devuyst   +19 more
doaj   +1 more source

Índices veno-arteriais para predição da acidemia fetal ao nascimento em gestações com insuficiência placentária Venous-arterial indices in the prediction of acidemia at birth in pregnancies with placental insufficiency

Revista Brasileira de Ginecologia e Obstetrícia, 2004
OBJETIVOS: investigar a possibilidade da predição da acidemia no nascimento, em gestações com insuficiência placentária, com o emprego de índices veno-arteriais avaliados pela dopplervelocimetria, definindo seus pontos de corte para esta predição ...
Francisco Herlânio Costa Carvalho, Antonio Fernandes Moron, Rosiane Mattar, Carlos Geraldo Viana Murta, Renato Martins Santana, Maria Regina Torloni, Luiz Kulay Junior   +6 more
doaj   +1 more source

Factors Associated with Initial Treatment Failure in Inpatients with Exacerbation of Chronic Obstructive Pulmonary Disease: A Cohort Study

International Journal of COPD
Noriko Kohyama,1 Kuniaki Hirai,2 Hironori Sagara,2 Miki Takenaka Sato,1 Masayuki Ohbayashi,1 Mari Kogo1 1Division of Pharmacotherapeutics, Department of Clinical Pharmacy, Showa Medical University School of Pharmacy, Tokyo, Japan; 2Division of ...
Kohyama N, Hirai K, Sagara H, Sato MT, Ohbayashi M, Kogo M   +5 more
doaj  

First National Expanded Genomic Newborn Screening Program in Qatar; A Pilot Study, Doha‐Heidelberg Collaboration

American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2374-2380, October 2026.
Reem Alsulaiman, Sarah Okashah, Radja Messai Badji, Fatemeh Abbaszadeh, Yaser Alsarraj, Rehab Ali Abdulrahman, Noora Shahbeck, Thalib Moideen, Reema El Hassan, Fatima Al‐Hamaydeh, Einas Alkuwari, Said Ismail, Hilal Al‐ Rifai, Ghassan Abdoh, Christian P. Schaaf, Georg Hoffmann, Saad Al‐Kaabi, Wadha Al‐Muftah, Tawfeg Ben‐Omran   +18 more
wiley   +1 more source