Results 131 to 140 of about 122,020 (253)

Differential effects of lysophospholipid headgroups, acyl chain length and saturation on vacuole acidification, Ca²⁺ transport, membrane fluidity, and fusion. [PDF]

Front Cell Dev Biol
Zhang C, Feng Y, Calderin JD, Failla V, Balutowski A, Ahmed R, Knapp C, Shah V, Grudzien D, Karat JM, Foley E, Fratti RA.   +11 more
europepmc   +1 more source

Microblasting Wound Dressings Mechanically Disrupt Polymicrobial Biofilms to Enhance Healing in Treatment‐Resistant Wounds

Advanced Science, EarlyView.
Treatment‐resistant wounds caused by polymicrobial biofilms are refractory to conventional therapies due to the dense extracellular matrices. We developed μBLAST, a microblasting wound dressing that combines MnO2‐doped biosilica and a H2O2‐releasing mesh to generate localized oxygen microbubbles that mechanically disrupt biofilms.
Yujin Ahn, Joo Hun Lee, Christian Hurd, Jiye Lee, Junggeon Park, Adam A. Markowicz, Zheyuan Zhang, Joanne Hwang, Guillermo L. Monroy, Simon A. Rogers, Woonggyu Jung, Stephen A. Boppart, Hyunjoon Kong   +12 more
wiley   +1 more source

Acidification

Dynamiques environnementales info, 2018
openaire   +2 more sources

Electrostatic Protein-Polysaccharide Assembly as a Potential Alternative to Ionic Gelation for Millimeter-Scale Hydrogel Beads: Insights into Accelerated Gelation from an Amaranth Protein-Xanthan Gum System. [PDF]

Gels
Cortez-Trejo MDC, Román-Doval R, Abadía-García L, Mendoza SO, Amaya-Llano SL.   +4 more
europepmc   +1 more source

Interfacial Proton‐Relay Microenvironment Enables Self‐Driven Singlet Oxygen Generation under Neutral Conditions

Advanced Science, EarlyView.
An interfacial proton‐relay microenvironment at MoS2‐CuCl heterostructures enables selective O2 activation to 1O2 under neutral conditions. Electron‐deficient sulfur sites mediate proton transfer to Cu‐bound O2, accelerating *OOH hydrogenation while suppressing O─O bond cleavage, achieving stable, efficient pollutant removal.
Qiaoyu Gao, Xiaohui Dai, Jian Ye, Lili Li, Chenxiao Yu, Yuehan Jiang, Jiangdong Dai, Xiaohua Tian, Jun Zhao, Jianming Pan   +9 more
wiley   +1 more source

Targeting lysosomal pH restores mitochondrial quality control in GBA1-mutant Parkinson's disease. [PDF]

Transl Neurodegener
Sheshadri P, Costa-Besada MA, Fisher A, Kiraly S, Singh K, Kourouzidou I, Blacker TS, Zeng J, Shirihai OS, Grinstaff MW, Duchen MR.   +10 more
europepmc   +1 more source

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Lactic acid drives NLRP3 inflammasome activation and caspase-1-like cytokine cleavage via intracellular acidification. [PDF]

Cell Death Dis
Lin HA, Lin HC, Tsai MH, Chen YJ, Bao BY, Tsai KJ, Shih CT, Yu JS, Chien KY, Huang KY, Ojcius DM, Chen LC.   +11 more
europepmc   +1 more source

All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species

Advanced Science, EarlyView.
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao, Abulaihaiti Tuergong, Hanshu Yang, Shuang Xue, An Yan, Mingzhen Wang, Weilong Song, Wenzhe Si, Ruixue Wang   +8 more
wiley   +1 more source

Conformational Fingerprints Underlying Thermal Modulation of PAC/TMEM206 Gating. [PDF]

Int J Mol Sci
Reyes-Lizana R, Fernández G, Duran-Morales S, Carrasco-Faus G, Duarte Y, Marquez-Miranda V, Díaz-Franulic I.   +6 more
europepmc   +1 more source