Results 171 to 180 of about 347,998 (329)

Sensitivity of acidified tamponed antigens in quality control test validation methodologies [PDF]

, 2022
Anderson Silva Dias, Mayra de Freitas Galvão, Guilherme Canhestro de Faria, George Afonso Vítor Caldeira   +3 more
openalex   +1 more source

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

Advanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei, Yuhan Lin, Xiu Liu, Xiaohong Zhu, Xiaowen Lu, Zhan Shi, Fan Jia, Shiqian Xu, Ling Fang, Lingling Jiang, Songying Zhang   +10 more
wiley   +1 more source

Microbicidal effects of slightly acidic hypochlorous acid water and weakly acidified chlorous acid water on foulbrood pathogens

, 2020
Ikuyo OHASHI, Kiyoko Kato, Mariko Okamoto, Sota Kobayashi, Daisuke Takamatsu   +4 more
openalex   +2 more sources

Investigation of acidification and changes in mineral element concentrations of Guizhou yellow soils in long-term tea plantations [PDF]

, 2023
Shaoxia Lin, Xiaolan Liu, Qiuxiao Yan, Fuxiao Wei, Daoping Wang   +4 more
openalex   +1 more source

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source

Ventilation and buffering capacity effects on ocean acidification in low oxygen environments. [PDF]

Nat Commun
Xue L, Sabine C, Chen J, Lauvset SK, Wei Q, Li K, Cai WJ.   +6 more
europepmc   +1 more source

Ocean Acidification Impairs Growth and Induces Oxidative Stress in the Macroalgae Ulva Fasciata and Petalonia Fascia

Fernanda Ribeiro de Freitas, Luis A. Barboza, Vitória Caroline Pereira Kühl, Ítalo Braga Castro, Milton Costa Lima Neto   +4 more
openalex   +1 more source

Substituted benzyl acetates: a new class of compounds that reduce gap junctional conductance by cytoplasmic acidification. [PDF]

, 1984
David C. Spray, Jeanne M. Nerbonne, Antônio Carlos Campos de Carvalho, Andrew L. Harris, Michael V. L. Bennett   +4 more
openalex   +1 more source

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

Advanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet, Sara Pugliese, Jordi Bruna, Daniel Ruiz‐Molina, Salvio Suárez‐García, Victor J. Yuste   +5 more
wiley   +1 more source

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

Advanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher, Victoria Lorant, Valerie Rochon, Abigail Carter, Cameron Stotts, My‐Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, Mireille I. Ouimet   +15 more
wiley   +1 more source