Results 231 to 240 of about 347,998 (329)

THE IMPACT OF PLANT MATERIAL FREEZING AND EXTRACTANT ACIDIFYING ON THE ANTIOXIDANT POTENTIAL AND PIGMENTS CONTENT IN EXTRACTS AND RAW MATERIALS OF DIFFERENT CARROT VARIETIES

, 2020
Anna Muzykiewicz-Szymańska, Joanna Zielonka-Brzezicka, Adam Klimowicz   +2 more
openalex   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Acidification-driven soil phosphorus fractionation following long-term fertilization and cessation at ukulinga mesic grassland in South Africa. [PDF]

Sci Rep
Buthelezi-Dube NN, Sithole Z.
europepmc   +1 more source

Soft‐Drug‐Inspired MnSTF Nano‐Adjuvant for Safe and Synergistic cGAS–STING Activation in Tumor Immunotherapy

Advanced Science, EarlyView.
This study introduces MnSTF, a soft‐drug‐inspired nanoadjuvant that overcomes the systemic toxicity of STING agonists. Through Mn2+ coordination with an ENPP1 inhibitor, it enables safe cGAS‐STING activation, remodels the tumor immune microenvironment, and synergizes with radiotherapy or vaccines to elicit robust antitumor immunity.
Guangfei Sun, Jiancheng Pan, Rui Li, Ruoxi Li, Ziyan Liu, Jinhui Wu, Tingsheng Lin, Yiqiao Hu, Ahu Yuan   +8 more
wiley   +1 more source

Developing indicators of risk to environmental variability based on species dependency in U.S. fishing communities in the Northeast and Southeast Regions. [PDF]

PLoS One
Seara T, McPherson M, Clay PM, Jepson M, Colburn LL, Weng C, Silva A.   +6 more
europepmc   +1 more source

Ocean acidification decreases molting but not survival of Antarctic amphipods Djerboa furcipes, Gondogeneia antarctica, and Prostebbingia gracilis [PDF]

Hannah E. Oswalt, Margaret O. Amsler, Charles D. Amsler, Julie B. Schram, James B. McClintock, Paul A. Baker   +5 more
openalex   +1 more source

The Microbiota Shapes Central Nervous System Myelination in Early Life

Advanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch, Emily G. Knox, Daniel Soong, Thomaz F. S. Bastiaanssen, Kalevi Trontti, Gabriel S. S. Tofani, Sophia Ivaschuk, Michael K. Collins, Donia Arafa, Jatin Nagpal, Iiris Hovatta, David A. Lyons, Gerard Clarke, John F. Cryan   +13 more
wiley   +1 more source

Carbon footprint and environmental impact of poultry manure valorization as organic composts. [PDF]

Poult Sci
Chen YN, Lin YC, Pan SY, Chang CH, Kuo TC.   +4 more
europepmc   +1 more source

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source

CLC3 regulates V-ATPase to enhance lysosomal degradation and cisplatin resistance in cervical cancer cells. [PDF]

Cell Death Discov
Chen C, Zhang F, Shen J, Zheng Q, Zhang Z, Lu S, Liu L, Zhu T, Du Y, Guan Y.   +9 more
europepmc   +1 more source