Results 41 to 50 of about 832,184 (288)

Trans-cerebral HCO3- and PCO2 exchange during acute respiratory acidosis and exercise-induced metabolic acidosis in humans [PDF]

, 2022
This study investigated trans-cerebral internal jugular venous-arterial bicarbonate ([HCO3-]) and carbon dioxide tension (PCO2) exchange utilizing two separate interventions to induce acidosis: 1) acute respiratory acidosis via elevations in arterial ...
MacLeod, David B., Drapeau, Audrey, Sekhon, Mypinder S., Carr, Jay MRJ, Smith, Kurt J, Hoiland, Ryan, Tymko, Michael M., Bain, Anthony R., Brassard, Patrice, Stacey, Benjamin, Howe, Connor, Bailey, Damian, Ainslie, Philip, Caldwell, Hannah G.   +13 more
core   +1 more source

Intraoperative Hyperkalemia Leading to Ventricular Tachycardia during Laparoscopic Renal Transplant [PDF]

Journal of Clinical and Diagnostic Research, 2018
Chronic kidney disease, consequent upon a variety of causes is a leading cause of morbidity and mortality. Renal transplantation is the preferred therapeutic approach for these patients.
Prachi Kadam, Unnati Bhatia, Mitali Patel   +2 more
doaj   +1 more source

Congenital bilateral abductor vocal cord palsy in previous cesarean section in pregnancy - a case report [PDF]

New Indian Journal of OBGYN, 2020
A 34 year old G2P1L1 at 35 weeks 6 days previous LSCS with bilateral congenital vocal cord palsy was referred to our tertiary care hospital with worsening of congenital stridor.
Meena Priyadharshini V, Grace Chrisilda Wesley, Chitra TV   +2 more
doaj   +1 more source

Causes of metabolic acidosis in canine hemorrhagic shock : role of unmeasured ions [PDF]

, 2007
Introduction: Metabolic acidosis during hemorrhagic shock is common and conventionally considered to be due to hyperlactatemia. There is increasing awareness, however, that other nonlactate, unmeasured anions contribute to this type of acidosis ...
Faithfull, N. Simon, Bruegger, Dirk, Jacob, Matthias, Keipert, Peter E., Becker, Bernhard F., Kristian B Packert, Rehm, Markus, Habler, Oliver P., Bernhard F Becker, Markus Rehm, Franz G Meisner, Meisner, Franz G., Oliver P Habler, Meisner, Franz Georg, Packert, Kristian B., Christoph J Wojtczyk, Packert, Kristian, Wojtczyk, Christoph J., Dirk Bruegger, Brügger, Dirk Steffen, Gregor I Kemming, Kemming, Gregor I., Habler, Oliver, Matthias Jacob, Peter E Keipert, N Simon Faithfull   +25 more
core   +1 more source

Risk factors for treatment failure of heated humidified high-flow nasal cannula as an initial respiratory support in newborn infants with respiratory distress

Pediatrics and Neonatology, 2020
Background: Humidified high-flow nasal cannula (HHFNC) has gained popularity because it is easier to use, more comfortable for babies, and advantageous for mother-infant bonding.
Won Young Lee, Eui Kyung Choi, Jeonghee Shin, Eun Hee Lee, Byung Min Choi, Young Sook Hong   +5 more
doaj   +1 more source

Metabolic acidosis may be as protective as hypercapnic acidosis in an ex-vivo model of severe ventilator-induced lung injury: a pilot study

BMC Anesthesiology, 2011
Background There is mounting experimental evidence that hypercapnic acidosis protects against lung injury. However, it is unclear if acidosis per se rather than hypercapnia is responsible for this beneficial effect.
Patsouris Efstratios, Agrogiannis George, Kopterides Petros, Metaxas Eugenios I, Siempos Ilias I, Kapetanakis Theodoros, Lazaris Andreas C, Stravodimos Konstantinos G, Roussos Charis, Armaganidis Apostolos   +9 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Inhalational sevoflurane in severe bronchial obstruction unresponsive to multipharmacologic therapy: a case report [v1; ref status: indexed, http://f1000r.es/Tg4qxg]

F1000Research, 2012
Introduction: Bronchial asthma with respiratory failure is a challenge for the intensivist as mechanical ventilation is often difficult due to bronchoconstriction and air-trapping.
Thomas Weber, Christian Schiebenpflug, Engelbert Deusch   +2 more
doaj   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source