Results 81 to 90 of about 143,662 (295)

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Clinical, Sonographic and Biochemical Profiles of Patients with a Mainz II Pouch Urine Diversion in Rural Uganda. A Case Series

International Medical Case Reports Journal
Fred Kirya,1 David Aderu,2 Joseph Epodoi,3 Denise Apolot,4 Ritah Kiconco,5 Richard Mpango,6 Jacob Eperu,1 Ronald Opito7 1Department of Surgery, School of Health Sciences, Soroti University, Soroti, Uganda; 2Department of Anatomy, School of Health ...
Kirya F, Aderu D, Epodoi J, Apolot D, Kiconco R, Mpango R, Eperu J, Opito R   +7 more
doaj  

Growth and developmental delay-hypotonia-vision impairment-lactic acidosis syndrome [PDF]

, 2020
INSERM
openalex   +1 more source

Modeling Supports Combinatorial Effects Between Pharmacological and Non‐Pharmacological Interventions to Prevent Opioid‐Induced Cardiac Arrest

Clinical Pharmacology &Therapeutics, EarlyView.
Few studies have quantified the effects of non‐pharmacological interventions (e.g., rescue breathing) in the setting of community opioid overdose. We extended a previously validated model for opioid antagonists by incorporating the mechanism of rescue breathing, and quantified combinatorial effects between rescue breathing and various formulations of ...
Bradlee Thrasher, John Mann, Anik Chaturbedi, Shilpa Chakravartula, Hamed Meshkin, Affan Affan, Alexander Galluppi, Ji Young Kim, Nigar Karimli, Yue Han, Zachary Dezman, Jeffry Florian, Zhihua Li   +12 more
wiley   +1 more source

Thiamine-Responsive Congenital Lactic Acidosis Without MC [PDF]

, 2005
J Gordon Millichap
openalex   +1 more source

The effect of preoperative sodium-glucose cotransporter 2 inhibitors on the incidence of perioperative metabolic acidosis: A retrospective cohort study [PDF]

, 2022
Yudai Iwasaki, Yusuke Sasabuchi, Sho Horikita, T Furukawa, Junji Shiotsuka, Alan Kawarai Lefor, Masamitsu Sanui   +6 more
openalex   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Targeted acidosis mediated delivery of antigenic MHC-binding peptides

Frontiers in Immunology
Cytotoxic T lymphocytes are the primary effector immune cells responsible for protection against cancer, as they target peptide neoantigens presented through the major histocompatibility complex (MHC) on cancer cells, leading to cell death.
Joey J. Kelly, Emily T. Ankrom, Sarah E. Newkirk, Damien Thévenin, Marcos M. Pires   +4 more
doaj   +1 more source

Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes

Epilepsia Open, EarlyView.
Abstract Genetic epilepsy with myoclonic seizures encompasses a heterogeneous spectrum of conditions, ranging from benign and self‐limiting forms to severe, progressive disorders. While their causes are diverse, a significant proportion stems from genetic abnormalities.
Antonietta Coppola, Marica Rubino, Antonella Riva, Pasquale Striano   +3 more
wiley   +1 more source

CRRT during TAE in Unstable Pelvic Fracture with Severe Lactic Acidosis [PDF]

, 2018
Chan Yong Park, Hyun Min Cho, Hoon Kwon, Chang Ho Jeon, Chang Won Kim   +4 more
openalex   +1 more source