Results 1 to 10 of about 41,340 (258)
New England Journal of Medicine, 2014 Lactic acidosis results from the accumulation of lactate and protons in the body fluids and is often associated with poor clinical outcomes. The effect of lactic acidosis is governed by its severity and the clinical context.
Jeffrey A Kraut +2 more
exaly +13 more sources
The Genomic Analysis of Lactic Acidosis and Acidosis Response in Human Cancers [PDF]
PLoS Genetics, 2008 The tumor microenvironment has a significant impact on tumor development. Two important determinants in this environment are hypoxia and lactic acidosis.
Joseph E Lucas +2 more
exaly +3 more sources
Type B Lactic Acidosis in A Child with Relapsed non-Hodgkin Lymphoma [PDF]
Journal of Pediatric Emergency and Intensive Care Medicine, 2023 Lactic acidosis is a major cause of metabolic acidosis in critically ill patients. Herein we report a child with relapsed non-Hodgkin’s lymphoma admitted to the pediatric intensive care unit (PICU) with profound lactic acidosis.
Gültaç Evren +5 more
core +2 more sources
Lactic acidosis occurrence during exercises in the smoke chamber in a 53-year-old firefighter with no significant medical history [PDF]
International Journal of Occupational Medicine and Environmental Health, 2014 Lactic acidosis is a form of metabolic acidosis with a high anion gap, reduced rate of arterial blood pH under 7.35 mmol/l, and lactic acid concentration over 7 mmol/l.
Spychalska, Magdalena +5 more
core +3 more sources
Etiology of lactic acidosis in malaria.
PLoS Pathogens, 2021 Lactic acidosis and hyperlactatemia are common metabolic disturbances in patients with severe malaria. Lactic acidosis causes physiological adverse effects, which can aggravate the outcome of malaria.
Philippe E Van den Steen +2 more
core +2 more sources
Dexamethasone associated with lactic acidosis in a stroke patient with meningioma-associated vasogenic edema: a case report. [PDF]
J Med Case RepBackground Corticosteroids are commonly used to manage a multitude of conditions, ranging from autoimmune to neurological diseases, including central nervous system vasculitis and vasogenic edema from large strokes.
Ser JS, Wee TC.
europepmc +2 more sources
Significant Lactic Acidosis from Albuterol [PDF]
Clinical Practice and Cases in Emergency Medicine, 2018 Lactic acidosis is a clinical entity that demands rapid assessment and treatment to prevent significant morbidity and mortality. With increased lactate use across many clinical scenarios, lactate values themselves cannot be interpreted apart from their ...
Maxwell Hockstein +3 more
core +3 more sources
Severe Lactic Acidosis in Decompensated Cirrhosis Despite Nondiagnostic Imaging. [PDF]
Clin Case RepABSTRACT Lactic acidosis is a strong predictor of mortality in cirrhosis, reflecting both impaired hepatic clearance and systemic tissue hypoxia. We describe a 38‐year‐old man with decompensated alcohol‐associated cirrhosis who developed severe lactic acidosis despite stable hemodynamics and initially nondiagnostic vascular imaging.
Ganju N +5 more
europepmc +2 more sources
Metformin Intoxication, Lactic Acidosis and Death: Case Report
Journal of Basic and Applied Research in Biomedicine, 2022 Metformin is an oral antidiabetic agent used as in the treatment of T2DM. A fearsome complication of the use of metformin is lactic acidosis. A nineteen-year-old woman was unconscious and cyanotic in her home.
Soylu, Hikmet +4 more
core +2 more sources
Lactic acidosis, hyperlactatemia and sepsis
Italian Journal of Medicine, 2016 Among hospitalized patients, lactic acidosis represents the most common cause of metabolic acidosis. Lactate is not just a metabolic product of anaerobic glycolysis but is triggered by a variety of metabolites even before the onset of anaerobic ...
Andrea Montagnani, Roberto Nardi
core +2 more sources