Results 71 to 80 of about 171,422 (307)

Fatal Mucormycosis Post COVID-19 Infection in Uncontrolled Diabetes with Misuse of Glucocorticoids and Antibiotics

open access: yesInfection and Drug Resistance, 2022
Heba Hamed,1 Raed Madia,2 Hosniyeh Ladadweh,2 Hiba Falana,2 Abdallah Damin AbuKhalil2 1Palestine Medical Complex, Ministry of Health, Ramallah, Palestine; 2Pharmacy Department, Faculty of Pharmacy, Nursing and Health Professions, Birzeit University ...
Hamed H   +4 more
doaj  

High flow nasal cannula versus noninvasive ventilation in the treatment of acute hypercapnic respiratory failure: A systematic review and meta‐analysis

open access: yesThe Clinical Respiratory Journal, 2023
Chronic obstructive pulmonary disease can lead to acute hypercapnic respiratory failure (AHRF), often treated using noninvasive ventilation (NIV). Emerging research suggests the potential utility of high flow nasal cannula (HFNC) for AHRF.
Aisling C. Fahey   +3 more
doaj   +1 more source

Therapeutic Peptide‐Programmed Liquid‐Crystalline Topology Switching for pH‐Gated Postoperative Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
A VDAP‐programmed liquid‐crystalline depot enables pH‐responsive postoperative immunotherapy for triple‐negative breast cancer. VDAP stabilizes a leakage‐resistant HII mesophase through peptide–lipid electrostatic assembly, whereas tumor acidosis unlocks the matrix and promotes graded topology remodeling toward a bicontinuous Im3̄m cubic phase for ...
Yan Yan   +12 more
wiley   +1 more source

ACIDOSIS [PDF]

open access: yesSouthern Medical Journal, 1918
n ...
openaire   +2 more sources

Lactate Homeostasis Disruption Potentiates TACE‐Immunotherapy in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
Lactate homeostasis is disrupted through spatially coordinated extracellular neutralization and intracellular acidification, triggering calcium overload, mitochondrial dysfunction, and immunogenic cell death. This metabolic reprogramming alleviates the immunosuppressive tumor microenvironment and enhances immune checkpoint blockade, providing a ...
Minjiang Chen   +12 more
wiley   +1 more source

Factors associated with lactic acidosis in HIV patients on antiretroviral therapy in Harare city- 2012

open access: yes, 2019
Introduction: Antiretroviral medicines have side effects that can be life threatening. An unpublished study by Malunga in Harare City, showed a high incidence of hyperlactatemia in patients on stalanev.
Choto, Emmaculate
core   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

open access: yes
Arthritis Care &Research, EarlyView.
Catherine Deffendall   +6 more
wiley   +1 more source

Implantable Systems for Cardiovascular Treatment and Monitoring: Comparative Insights From Intracardiovascular and Extracardiovascular Technologies

open access: yesAdvanced Intelligent Systems, EarlyView.
A unifying device–cardiovascular interface framework is presented to classify implantable cardiovascular technologies as intracardiovascular blood‐contacting systems or extracardiovascular tissue‐only and blood‐handling architectures. Cross‐class comparison across shared semiquantitative criteria, including blood‐contact burden, biomimicry ...
Bergo Nicolò   +7 more
wiley   +1 more source

Immune Modulatory Therapy for Severe Dengue Hemorrhagic Fever in a Patient With Mitochondrial Complex I Deficiency: A Case Report

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Dengue virus (DENV) poses a serious global health challenge, particularly in cases of dengue hemorrhagic fever (DHF). Patients with preexisting mitochondrial disorders may be at increased risk for complications due to the specific impact of DENV on mitochondrial‐dependent cellular processes and immune function.
Audra N. Iness   +11 more
wiley   +1 more source

A Novel Model of Cancer Drug Resistance: Oncosomal Release of Cytotoxic and Antibody-Based Drugs

open access: yesBiology, 2020
Extracellular vesicles (EVs), such as exosomes or oncosomes, often carry oncogenic molecules derived from tumor cells. In addition, accumulating evidence indicates that tumor cells can eject anti-cancer drugs such as chemotherapeutics and targeted drugs ...
Takanori Eguchi   +3 more
doaj   +1 more source

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