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Renal Tubular Acidosis

Annual Review of Medicine, 1969
Renal tubular acidosis (RTA) represents a clinical syndrome characterized by a state of renal tubular insufficiency with regard to the reabsorption of bicarbonate, the excretion of net hydrogen ion, or both, and includes a large number of etiologies. In this condition, in contradistinction to the so-called glomerular acidosis, glomerular function is ...
J, Rodriguez-Soriano, C M, Edelmann
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Renal Tubular Acidosis

Pediatric Clinics of North America, 2019
Renal tubular acidosis should be suspected in poorly thriving young children with hyperchloremic and hypokalemic normal anion gap metabolic acidosis, with/without syndromic features. Further workup is needed to determine the type of renal tubular acidosis and the presumed etiopathogenesis, which informs treatment choices and prognosis.
Robert Todd, Alexander, Martin, Bitzan
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Renai Tubular Acidosis

Endocrinology and Metabolism Clinics of North America, 1990
Renal tubular acidosis refers to a group of disorders that result from pure tubular damage without concomitant glomerular damage. They could be hereditary (primary) or acquired (secondary to various disease states like sickle cell disease, obstructive uropathy, postrenal transplant, autoimmune disease, or drugs).
M, Rothstein, C, Obialo, K A, Hruska
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Hyperammonemia associated with distal renal tubular acidosis or urinary tract infection: a systematic review

open access: yesPediatric Nephrology, 2017
Background: Hyperammonemia usually results from an inborn error of metabolism or from an advanced liver disease. Individual case reports suggest that both distal renal tubular acidosis and urinary tract infection may also result in hyperammonemia ...
Gregorio P Milani, Sebastiano A G Lava
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Renal Tubular Acidosis

Dimensions of Critical Care Nursing, 2010
Renal tubular acidosis is a relatively uncommon clinical syndrome characterized by the inability of the kidney to adequately excrete hydrogen ions, retain adequate bicarbonate, or both. This syndrome can be categorized into 3 separate disorders, each with unique clinical characteristics.
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Pregnancy and Renal Tubular Acidosis

American Journal of Perinatology, 1999
Renal tubular acidosis (RTA) is uncommonly encountered in pregnancy. The risk for these women to develop pregnancy-induced hypertension has not been previously described. The renal defect noted in these women, aggravated by the normal hypervolemia of pregnancy, may predispose to hypertension.
T F, Rowe, K, Magee, F G, Cunningham
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Distal renal tubular acidosis

Current Opinion in Pediatrics, 2004
Research in the past several years has led to the understanding of numerous genetic mutations that lead to inheritable forms of distal renal tubular acidosis (dRTA). Most of these mutations affect the physiology of the A-intercalated cells of the renal cortical collecting duct.
Julie A, Nicoletta, George J, Schwartz
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FAMILIAL RENAL TUBULAR ACIDOSIS

Annals of Internal Medicine, 1961
Excerpt Acidosis of renal origin is an increased hydrogen ion concentration due to an impairment in the excretion of titratable acid and/or ammonium ion, to an excessive excretion of bicarbonate, o...
R E, RANDALL, W H, TARGGART
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Inherited renal tubular acidosis

Current Opinion in Nephrology and Hypertension, 2000
The past few years have witnessed great progress in elucidating the molecular basis of inherited renal tubular acidosis. Consistent with the physiologically defined importance of multiple gene products in urinary acidification, heritable renal tubular acidosis is genetically heterogeneous.
C, Shayakul, S L, Alper
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FAMILIAL RENAL TUBULAR ACIDOSIS

Annals of Internal Medicine, 1968
Excerpt To the Editor:I was interested to read the editorial note on familial renal tubular acidosis (RTA) by Dr. Vardaman M. Buckalew (Ann. Intern. Med. 68: 1367, 1968).
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