Results 101 to 110 of about 2,583,428 (314)

The Staphylococcus aureus Response to Unsaturated Long Chain Free Fatty Acids: Survival Mechanisms and Virulence Implications.

open access: yes, 2009
Staphylococcus aureus is an important human commensal and opportunistic pathogen responsible for a wide range of infections. Long chain unsaturated free fatty acids represent a barrier to colonisation and infection by S.
Horsburgh Malcolm J.   +26 more
core   +1 more source

Chemically Fuelled Deracemization of Amino Acids [PDF]

open access: yes, 2022
openSystems that work out-of-equilibrium are common in nature, living organisms are the most striking example of that. Chemists are trying to mimic living organisms because of the multitude of properties that might be implemented in synthetic systems ...
DEL VECCHIO, ALICE
core  

Control y tratamiento médico por ingestión de sustancias cáusticas Control and medical treatment for ingestion of caustic substances

open access: yesMedisan, 2010
Se comunica brevemente lo más actual sobre el control y tratamiento médico por la ingestión de sustancias cáusticas como ácidos y álcalis, así como de las personas que ingieren drogas con el objetivo de transportarlas de forma ilegal.A short report is ...
José Manuel Ricardo Ramírez
doaj  

Effect of Steric Constraint at the γ-Backbone Position on the Conformations and Hybridization Properties of PNAs

open access: yesJournal of Nucleic Acids, 2011
Conformationally preorganized peptide nucleic acids (PNAs) have been synthesized through backbone modifications at the γ-position, where R = alanine, valine, isoleucine, and phenylalanine side chains. The effects of these side-chains on the conformations
Matthew J. Crawford   +4 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Endogenous Ribonucleases: Therapeutic Targeting of the Transcriptome Through Oligonucleotide-Triggered RNA Inactivation

open access: yesBiomolecules
The selective regulation of gene expression at the RNA level represents a rapidly evolving field offering substantial clinical potential. This review examines the molecular mechanisms of intracellular enzymatic systems that utilize single-stranded ...
Daria A. Chiglintseva   +2 more
doaj   +1 more source

Changes of main organic acids during vinification.

open access: yesKvasný průmysl, 2001
In climate conditions of Czech and Moravian wine region there is usually higher content of lower organic acids than in the regions situated sounthing. Content of tartaric acid is the highest in the grapes, during vinification continuously decrease. Malic
K. ŠTEFECOVÁ, J. ČEPIČKA
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

The synthesis of substituted phosphonic acids [PDF]

open access: yes
Cyclic phosphonic acid analogues of the endogenous amino acids L-aspartic acid and L -glutamic acid have played a major role in the characterisation of excitatory amino acid receptors in the central nervous system. The aim of the first section of this
Hanrahan, Jane
core  

Home - About - Disclaimer - Privacy