Results 41 to 50 of about 4,066,847 (276)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Quest for space: Tenacity of DNA, Protein, and Lipid macromolecules in intracellular crowded environment

open access: yesBiomolecular Concepts
The biochemical processes in the cellular milieu involving biomacromolecular interaction usually occur in crowded and heterogeneous environments, impacting their structure, stability, and reactivity.
Phogat Priyanka   +5 more
doaj   +1 more source

Self-association of Coralyne: An ordered thermal destacking

open access: yesResults in Chemistry, 2020
Understanding DNA-ligand interactions is a prerequisite, for designing sequence/structure specific ligands. Generally, stabilization/destabilization of DNA structures as a function of ligand is studied using UV-thermal melting, and the data is usually ...
Shikha Kaushik   +3 more
doaj   +1 more source

Incorporation in vitro of labeled amino acids into bone marrow cell proteins [PDF]

open access: yes, 1950
Nearly all experiments on the incorporation of labeled amino acids into tissue proteins in vitro have been done on tissues whose cell structure has been partially or completely disintegrated, e.g. tissue slices, segments, or homogenates.
Borsook, Henry   +4 more
core  

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Exploring potential of i-motif DNA formed in the promoter region of GRIN1 gene for nanotechnological applications

open access: yesResults in Chemistry, 2020
The tandem repeat stretches of cytosine residues fold to construct intercalated motif (i-motif) structures over an acidic pH range. Several advancements have been made to understand the biological role of i-motif DNA.
Swati Chaudhary   +3 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Commercial varieties of European plums grown in Hungary, a comparison of promising foreign varieties with the widely grown traditional ones

open access: yesInternational Journal of Horticultural Science, 2012
Observations and investigations performed in laboratory at several growing sites over a period of many years are summarised on established plum varieties as well as on new promising ones concerning their marketing value.
Sz. Kovács   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Dual miRNases for Triple Incision of miRNA Target: Design Concept and Catalytic Performance

open access: yesMolecules, 2020
Irreversible destruction of disease-associated regulatory RNA sequences offers exciting opportunities for safe and powerful therapeutic interventions against human pathophysiology.
Olga Patutina   +6 more
doaj   +1 more source

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