Results 71 to 80 of about 2,583,428 (314)

Age-related changes of muscle and plasma amino acids in healthy children

, 2010
The aim of the study was to explore if changes in muscle and plasma amino acid concentrations developed during growth and differed from levels seen in adults.
Andersson, Kerstin,, Wernerman, Jan,, Hammarqvist, Folke,, Angsten, Gertrud,, Meurling, Staffan,   +4 more
core   +1 more source

Characterization of Cupriavidus eutrophus В-10646 Culture Synthesizing Polyhydroxyalkanoates Grown on Sugars And Lipidic Substrates [PDF]

Журнал Сибирского федерального университета: Серия Биология, 2014
Growth, polyhydroxyalkanoates (PHAs) accumulation and total fatty acid composition of the lipids of Cupriavidus eutrophus B-10646 were studied, using various carbon sources (fructose, glucose, oleic acid, sunflower seed oil).
Natalia O. Zhila, Tatiana G. Volova, Galina S. Kalacheva   +2 more
doaj  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Replacement of dietary saturated fatty acids by trans fatty acids lowers serum HDL cholesterol and impairs endothelial function in healthy men and women

, 2001
We tested whether trans fatty acids and saturated fatty acids had different effects on flow-mediated vasodilation (FMD), a risk marker of coronary heart disease (CHD). Consumption of trans fatty acids is related to increased risk of CHD, probably through
Roos, N.M., de, Katan, M.B., Bots, M.L.
core  

Omega 3 fatty acids and cognitive health in older people. [PDF]

, 2012
Oily fish and other sources of long-chain n-3 polyunsaturated fatty acids (n-3 LCPs) have been proposed as protective against dementia and age related cognitive impairment.
Dangour, Alan, Uauy, Ricardo, Dangour, Alan D, Andreeva, Valentina, Andreeva, Valentina A, Sydenham, Emma   +5 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Induction of cardiac Angptl4 by dietary fatty acids is mediated by peroxisome proliferator-activated receptor beta/delta and protects against fatty acid-induced oxidative stress

, 2010
Although dietary fatty acids are a major fuel for the heart, little is known about the direct effects of dietary fatty acids on gene regulation in the intact ...
Degenhardt, Tatjana, Boekschoten, M.V., Kersten, A.H., Boekschoten, Mark V., Georgiadi, Anastasia, Lichtenstein, Laeticia, Müller, Michael, Georgiadi, A., Bilsen, M., van, van Bilsen, Marc, Müller, M.R., Lichtenstein, L.L., Desvergne, Beatrice, Degenhardt, T., Desvergne, B., Boekschoten, Mark V, van Bilsen, M., Kersten, Sander   +17 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The inhibition of T-lymphocyte proliferation by fatty acids is via an eicosanoid-independent mechanism

, 1992
Eicosanoids, in particular prostaglandin E2 (PGE2), are potent inhibitors of a number of immune responses, including lymphocyte proliferation. We have previously shown that fatty acids, especially polyunsaturated fatty acids (PUFA), inhibit mitogen ...
Calder, P.C., Newsholme, E.A., Bevan, S.J.   +2 more
core