Results 101 to 110 of about 251,367 (400)
The roles of history, chance, and natural selection in the evolution of antibiotic resistance
eLife, 2021 History, chance, and selection are the fundamental factors that drive and constrain evolution. We designed evolution experiments to disentangle and quantify effects of these forces on the evolution of antibiotic resistance.
Alfonso Santos-Lopez +5 more
doaj +1 more source
Epidemiology of antibiotic resistance in culture-positive hospitalized patients in selected hospitals in Khartoum, Sudan [PDF]
, 2019 Objective: To study the prevelence of antibiotic resistance and the prevalent bacterial isolates in hospitalized patients in Khartoum hospitals. Materials & Methods: A cross-sectional prevalence study was carried out during the period of April ...
Abdalrahman, Ihab B +3 more
core +4 more sources
Acinetobacter infections: Overview and treatment dilemma
CHRISMED Journal of Health and Research, 2020 Introduction: Acinetobacter species are known to cause serious hospital-acquired infections (HAIs), especially in the intensive care unit (ICU). The aim of this study is to estimate the burden of such infections and also to determine their sensitivity to
Sana Ali
doaj +1 more source
A transcriptional regulatory mechanism finely tunes the firing of type VI secretion system in response to bacterial enemies [PDF]
, 2017 The ability to detect and measure danger from an environmental signal is paramount for bacteria to respond accordingly, deploying strategies that halt or counteract potential cellular injury and maximize survival chances. Type VI secretion systems (T6SSs)
Feldman, Mario F +2 more
core +2 more sources
The Mechanisms of Disease Caused by Acinetobacter baumannii
Frontiers in Microbiology, 2019 Acinetobacter baumannii is a Gram negative opportunistic pathogen that has demonstrated a significant insurgence in the prevalence of infections over recent decades. With only a limited number of “traditional” virulence factors, the mechanisms underlying
Faye C. Morris +4 more
semanticscholar +1 more source
Advanced Science, EarlyView.BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang +9 more
wiley +1 more source
The Pan African Medical Journal, 2019 INTRODUCTION: Infection due to multidrug-resistant microorganisms is a growing threat in healthcare settings. Acinetobacter species specifically A. baumannii is increasingly becoming resistant to most antimicrobial agents recommended for treatment.
Victor Moses Musyoki +5 more
doaj +1 more source
Comparative transcriptomics of multidrug-resistant Acinetobacter baumannii in response to antibiotic treatments [PDF]
, 2018 Multidrug-resistant Acinetobacter baumannii, a major hospital-acquired pathogen, is a serious health threat and poses a great challenge to healthcare providers.
Chan, Ting-Fung +8 more
core +2 more sources
Journal of Medical Microbiology, 2014 Acinetobacter baumannii, Acinetobacter nosocomialis and Acinetobacter pittii are clinically relevant members of the Acinetobacter calcoaceticus–A. baumannii (Acb) complex and important nosocomial pathogens. These three species are genetically closely related and phenotypically similar; however, they differ in their epidemiology ...
Te-Li, Chen +5 more
openaire +2 more sources
Advanced Science, EarlyView.Traditionally considered sterile, the articular cavity is now recognized to harbor microbial communities influencing osteoarthritis (OA). Integrating 16S rRNA sequencing and culturomics, Micrococcus luteus is enriched in advanced OA. Notably, M. luteus G18 exacerbates cartilage degeneration via TLR2/JNK/AP‐1‐mediated ECM disruption, revealing intra ...
Tingtao Chen +6 more
wiley +1 more source