Results 81 to 90 of about 237,056 (345)

High-dose Sulbactam Treatment for Ventilator-Associated Pneumonia Caused by Carbapenem-Resistant [PDF]

Korean Journal of Critical Care Medicine, 2016
Background Several antibiotics can be used to treat ventilator-associated pneumonia caused by carbapenem-resistant A. baumannii (CRAB-VAP) including high-dose sulbactam. However, the effectiveness of high-dose sulbactam therapy is not well known.
In Beom Jeong, Moon Jun Na, Ji Woong Son, Do Yeon Jo, Sun Jung Kwon   +4 more
doaj   +1 more source

In vitro activity of curcumin in combination with epigallocatechin gallate (EGCG) versus multidrug-resistant Acinetobacter baumannii [PDF]

, 2014
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Betts, JW, Wareham, DW
core   +2 more sources

Large increase in bloodstream infections with carbapenem-resistant Acinetobacter species during the first 2 years of the COVID-19 pandemic, EU/EEA, 2020 and 2021

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2022
Recent data from the European Antimicrobial Resistance Surveillance Network (EARS-Net) show a large increase of +57% in Acinetobacter species bloodstream infections in the European Union and European Economic Area in the first years of the COVID-19 ...
P. Kinross, C. Gagliotti, H. Merk, D. Plachouras, D. Monnet, L. Högberg, R. Strauss, K. Mertens, Stefana Sabtcheva, A. Andrašević, Panagiota Maikanti, H. Žemličková, H. Hasman, M. Ivanova, Kati Räisänen, S. Maugat, I. Noll, K. Mellou, Á. Tóth, K. Helgason, S. Murchan, G. Errico, Ieva Voita, Esther Walser-Domjan, Jolanta Miciuleviciene, M. Perrin, E. Scicluna, S. H. Woudt, Ørjan Samuelsen, D. Żabicka, M. Caniça, G. Popescu, Eva Schréterová, H. Ribič, Maria Belén Aracil García, H. Billström   +35 more
semanticscholar   +1 more source

Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response

Advanced Science, EarlyView.
This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai, Mengping He, Jianya Luo, Shuang Zhou, Tengyue Zhang, Jianing Li, Zhiqiang Wang, Yuan Liu   +7 more
wiley   +1 more source

Readmissions with multidrug-resistant infection in patients with prior multidrug resistant infection [PDF]

, 2017
OBJECTIVETo determine incidence of and risk factors for readmissions with multidrug-resistant organism (MDRO) infections among patients with previous MDRO infection.DESIGNRetrospective cohort of patients admitted between January 1, 2006, and October 1 ...
Babcock, Hilary M, Burnham, Jason P, Kollef, Marin H, Kwon, Jennie H, Olsen, Margaret A   +4 more
core   +2 more sources

Characterization of carbapenem resistance in environmental samples and Acinetobacter spp. isolates from wastewater and river water in Poland.

Science of the Total Environment, 2022
The aim of this study was to analyze the prevalence of carbapenem resistance genes in Acinetobacter spp. isolated from wastewater in a municipal WWTP and to determine their spread from treated wastewater to river water with the use of conventional and ...
Jakub Hubeny, E. Korzeniewska, Martyna Buta-Hubeny, W. Zieliński, Damian Rolbiecki, M. Harnisz   +5 more
semanticscholar   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

Advanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang, Zhongwei Yang, Yunfan Zhang, Longwei Wang, Xiaoyu Zhang, Jiahui Mao, Yizhi Dai, Yifan Yuan, Mingge Wang, Xin Yang, Xin Yu, Jing Liu, Chunying Chen   +12 more
wiley   +1 more source

Draft Genome Sequence of an International Clonal Lineage 1 Acinetobacter baumannii Strain from Argentina [PDF]

, 2014
In the last few years Acinetobacter baumannii has emerged worldwide as an important nosocomial pathogen in medical institutions. Here, we present the draft genome sequence of the international clonal lineage 1 (ICL1) A.
Centron, Daniela, Déraspe, Maxime, Ramirez, Maria Soledad, Roy, Paul H., Traglia, German Matias, Vilacoba, Elisabet   +5 more
core   +1 more source

DOTA‐grafted Cationic Polymers Behaving as Powerful Macromolecular Resistance‐reversal Agents (MRRAs) Combating Against New Delhi Metallo‐β‐lactamase (NDM)‐producing Bacteria

Advanced Science, EarlyView.
Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang, Jian Zhang, Yun li, Liping Qiao, Zhuorui Dong, Dandan Cui, Peirong Bai, Liping Li, Bing Cao, Ruiping Zhang   +9 more
wiley   +1 more source

Acinetobacter Strain KUO11TH, a Unique Organism Related to Acinetobacter pittii and Isolated from the Skin Mucus of Healthy Bighead Catfish and Its Efficacy Against Several Fish Pathogens

Microorganisms, 2019
The bacterial strain KU011TH was isolated from the skin mucus of healthy bighead catfish. The strain is a Gram-negative coccobacillus that is nonmotile, aerobic, catalase positive, oxidase negative, and nonhemolytic. Sequence analyses of the housekeeping
Anurak Bunnoy, Uthairat Na-Nakorn, Pattanapon Kayansamruaj, Prapansak Srisapoome   +3 more
doaj   +1 more source