Results 61 to 70 of about 203,061 (356)

Chemical Synthesis of Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii Capsular Polysaccharide Fragments as Leads for Cross‐Protection

Angewandte Chemie, EarlyView.
A total of 16 chemically synthesized capsular polysaccharide (CPS) fragments related to Pseudomonas aeruginosa, Staphylococcus aureus, and Acinetobacter baumannii were analyzed by glycan microarray. Comparative screening revealed three conserved epitopes that act as cross‐protective vaccine lead candidates against multidrug‐resistant (MDR) bacterial ...
Amar Kumar Mishra, Emelie E. Reuber, Diksha Rai, Leif E. Sander, Julia Duerr, Simon Y. Graeber, Marcus A. Mall, Bettina C. Fries, Peter H. Seeberger, Suvarn S. Kulkarni   +9 more
wiley   +2 more sources

Co-production of ESBL and AmpC β-Lactamases in Clinical Isolates of A. baumannii and A. lwoffii in a Tertiary Care Hospital From Northern India [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background: Acinetobacter baumannii is an important cause of health care associated infections which are difficult to control and treat, because of widespread antimicrobial resistance which is possessed by this organism.
Pooja Singla, Rama Sikka, Antariksh Deeep, Deep Gagneja, Uma Chaudhary   +4 more
doaj   +1 more source

Human Pleural Fluid Elicits Pyruvate and Phenylalanine Metabolism in Acinetobacter baumannii to Enhance Cytotoxicity and Immune Evasion [PDF]

, 2019
The CCAAT box-harboring proteins represent a family of heterotrimeric transcription factors which is highly conserved in eukaryotes. In fungi, one of the particularly important homologs of this family is the Hap complex that separates the DNA-binding ...
Bonomo, Robert A., Brennan, Catherine A., Dang, Emily, Fernandez, Jennifer, Fung, Sammie, Harris, Caitlin M., Jimenez, Verónica, Liu, Christine, Martinez, Jasmine, Mendoza, Anthony M., Myers, Amber L., Nakanouchi, Jun, Nikolaidis, Nikolas, Nyah, Rodman, Ramirez, Maria Soledad, Sieira, Rodrigo   +15 more
core   +1 more source

Balanced Expression of the Diiron Oxygenase BioE Is Essential for Biotin Homeostasis in Elizabethkingia meningoseptica

Advanced Science, EarlyView.
BioE is a new diiron oxygenase that catalyzes the conversion of long‐chain acyl groups into pimeloyl thioester, initiating biotin synthesis. The overexpression of EmBioE disrupts lipid metabolic homeostasis, requiring repressor BioL to maintain a balance between long‐chain fatty acids and biotin synthesis.
Meng Zhang, Ying‐ying Fu, Xiaoqiang Yang, Qiuying Qin, Xinyu Su, Jiaming Fang, Yanhua Kang, Qingwen He, Zhi Ruan, Yongchang Xu   +9 more
wiley   +1 more source

Acinetobacter baumannii Biofilm Formation and Its Role in Disease Pathogenesis: A Review

Infection and Drug Resistance, 2021
Alemu Gedefie,1 Wondmagegn Demsis,1 Melaku Ashagrie,1 Yeshimebet Kassa,1 Melkam Tesfaye,1 Mihret Tilahun,1 Habtye Bisetegn,1 Zenawork Sahle2 1Department of Medical Laboratory Sciences, College of Medicine and Health Science, Wollo University, Dessie ...
Gedefie A, Demsis W, Ashagrie M, Kassa Y, Tesfaye M, Tilahun M, Bisetegn H, Sahle Z   +7 more
doaj  

Epidemiology of antibiotic resistance in culture-positive hospitalized patients in selected hospitals in Khartoum, Sudan [PDF]

, 2019
Objective: To study the prevelence of antibiotic resistance and the prevalent bacterial isolates in hospitalized patients in Khartoum hospitals. Materials & Methods: A cross-sectional prevalence study was carried out during the period of April ...
Abdalrahman, Ihab B, Al-Hassan, Leena, El Amin, Nagwa M, Osman, Einas A   +3 more
core   +4 more sources

MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts

Advanced Science, EarlyView.
We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang, Yuli Zhang, Zixin Kang, Jiayun Xiong, Ronghua Yang, Kang Ning   +5 more
wiley   +1 more source

Evaluation of the Sensitivity of Acinetobacter sp. burn isolates to Ciprofloxacin and some of other used antibiotics for treatment

فصلنامه دانشگاه علوم پزشکی جهرم, 2009
Introduction: Acinetobacter sp. is usually considered to be opportunistic pathogens.  They are often multi-resistant to antibiotics, meaning that therapy and infection control are complicated.
Nima Hosseini Jazani, Homayon Babazadeh, HamidReza Khalkhali   +2 more
doaj  

An overview of sulbactam‐durlobactam approval and implications in advancing therapeutics for hospital‐acquired and ventilator‐associated pneumonia by acinetobacter baumannii‐calcoaceticus complex: A narrative review

Health Science Reports
Purpose Infections caused by Acinetobacter baumannii, particularly those resistant to antibiotics such as carbapenem, have become a global health crisis with a significant mortality rate.
Ayush Anand, Amogh Verma, Sarabjeet Kaur, Priyangi Kathayat, Rachel M. Manoj, Aakanksha Aakanksha, Justice K. Turzin, Prakasini Satapathy, Mahalaqua N. Khatib, Shilpa Gaidhane, Quazi S. Zahiruddin, Neelima Kukreti, Sarvesh Rustagi, Arihant Surana   +13 more
doaj   +1 more source

A transcriptional regulatory mechanism finely tunes the firing of type VI secretion system in response to bacterial enemies [PDF]

, 2017
The ability to detect and measure danger from an environmental signal is paramount for bacteria to respond accordingly, deploying strategies that halt or counteract potential cellular injury and maximize survival chances. Type VI secretion systems (T6SSs)
Feldman, Mario F, Lazzaro, Martina, Vescovi, Eleonora Garcia   +2 more
core   +2 more sources