Results 81 to 90 of about 143,834 (302)

DOTA‐grafted Cationic Polymers Behaving as Powerful Macromolecular Resistance‐reversal Agents (MRRAs) Combating Against New Delhi Metallo‐β‐lactamase (NDM)‐producing Bacteria

Advanced Science, EarlyView.
Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang, Jian Zhang, Yun li, Liping Qiao, Zhuorui Dong, Dandan Cui, Peirong Bai, Liping Li, Bing Cao, Ruiping Zhang   +9 more
wiley   +1 more source

Comparison of Various Phenotypic Methods in Detection of Carbapenemases and Metallo-Beta-Lactamases (MBL) in Carbapenem Resistant Clinlical Isolates of Acinetobacter Species at A Tertiary Care Centre [PDF]

Journal of Research in Applied and Basic Medical Sciences, 2022
Background & Aims:  carbapenem-resistant strains of Acinetobacter baumannii (A. baumannii) have been reported worldwide over the last decade. Detection of the carbapenemases is crucial to determine the severity of the problem. The aim of our study was to
Mariya Rouf, Asifa Nazir, Ovais Karnain, Shahida Akhter   +3 more
doaj  

A Genomic Catalog of Migratory Microbiomes from Wild Birds across China's Habitats

Advanced Science, EarlyView.
ABSTRACT Migratory birds play an important role in the spread of antimicrobial resistance (AMR); however, gaps in surveillance data from vital regions along migratory flyways across China limit the detection of emergent threats. Here, we assembled 340 metagenomes from 52 bird species covering 11 provincial administrative districts in China, presenting ...
Yanan Wang, Heqi Wu, Mengqi Qu, Chunge Zhang, Ziqian Xu, Yuhang Pei, Chaochao Zhao, Jiangtao Wang, Sufang Ma, Na Lyu, Xuebin Xu, Yuhai Bi, Baoli Zhu, George F. Gao   +13 more
wiley   +1 more source

The problem of global development of antibiotic resistant nosocomial pathogens

Терапевтический архив, 2020
The problem of global expansion of multidrug-resistant nosocomial infections pathogens is under special attention at the moment. Antibiotic resistance increasing give us the limited treatment options.
N. I. Gabrielyan, S. О. Sharapchenko, О. V. Kisil, V. G. Kormilitsina, I. V. Drabkina, Т. B. Safonova, М. I. Petrukhina, R. Sh. Saitgareev, V. М. Zakharevich   +8 more
doaj   +1 more source

Ribotyping of the Acinetobacter calcoaceticus-Acinetobacter baumannii complex [PDF]

Journal of Clinical Microbiology, 1992
The Acinetobacter calcoaceticus-Acinetobacter baumannii complex consists of four genotypically distinct but phenotypically very similar bacterial species or DNA groups: A. calcoaceticus (DNA group 1), A. baumannii (DNA group 2), unnamed DNA group 3 (P. J. M. Bouvet and P. A. D. Grimont, Int. J. Syst. Bacteriol.
openaire   +2 more sources

A rational strategy to optimize photodrugs by Molecular Dynamics simulations for killing drug‐resistant Gram‐negative bacteria

AIChE Journal, EarlyView.
Abstract Antimicrobial resistance has become a major threat to human health, particularly for Gram‐negative bacteria such as Acinetobacter baumannii and Klebsiella pneumoniae. Disruption of membrane integrity is regarded as a promising antimicrobial strategy that does not induce distinct drug resistance, while increasing the internalization of drug ...
Lei Hao, Yeonho Song, Cheng Zhang, Yumei Wang, Haoying Ge, Wen Sun, Jingyun Wang, Jun Soo Kim, Xiaojun Peng, Juyoung Yoon, Haidong Li   +10 more
wiley   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Bioremediation of oil-contaminated soil containing elevated concentrations of sodium chloride and heavy metals

Трансформация экосистем
The study of the effect of heavy metals and sodium chloride on the oxidative activity of oil destructor strains of the genus Acinetobacter showed that the bacteria retain the ability to biodegrade oil at concentrations of lead and zinc ions up to 1000 ...
Kuzina E.V., Mukhamatdyarova S.R., Iskuzhina M.G., Sharipova Yu.Yu., Korshunova T.Yu.   +4 more
doaj   +1 more source

Comparative Study for Detection of Carbapenemase Producers among Non-fermenting Gram Negative Uropathogens with Special Reference to Risk Factors and Fosfomycin Susceptibility [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Urinary Tract Infections (UTIs) are among the commonest type of bacterial infections. Non-Fermenting Gram-Negative Bacilli (NFGNB) are now emerging as important uropathogens.
Azza Z Labeeb, Asmaa M Elbrolosy
doaj   +1 more source

Acute Post-cataract Surgery Endophthalmitis and Corneal Ulcer with Acinetobacter Managed with Colistin: A Case Report

Journal of Research in Pharmacy Practice
Postoperative endophthalmitis is a rare but severe complication of phacoemulsification cataract surgery (PCS). Acinetobacter baumannii is an uncommon pathogen, often associated with multidrug resistance and poor outcomes.
Mohsen Pourazizi, Alireza Peyman, Alireza Dehghani, Asieh Aslani, Mahsa Pourmahdi-Boroujeni, Paria Sanei   +5 more
doaj   +1 more source