Results 41 to 50 of about 92,603 (242)

Biofilm is a major virulence determinant in bacterial colonization of chronic skin ulcers independently from the multidrug resistant phenotype [PDF]

, 2017
Bacterial biofilm is a major factor in delayed wound healing and high levels of biofilm production have been repeatedly described in multidrug resistant organisms (MDROs).
Bordignon, Valentina, Cavallo, Ilaria, Cilli, Laura, De Santis, Alessandra, Di Domenico, Enea Gino, Di Salvo, Fabiola, Ensoli, Fabrizio, Farulla, Ilaria, Gallo, Maria Teresa, La Parola, Ilaria Lesnoni, Pimpinelli, Fulvia, Pontone, Martina, Prignano, Grazia, Sperduti, Isabella, Toma, Luigi, Vespaziani, Matteo   +15 more
core   +2 more sources

Extended-Spectrum Cephalosporinase in Acinetobacter baumannii [PDF]

Antimicrobial Agents and Chemotherapy, 2010
ABSTRACT An AmpC-type β-lactamase conferring high-level resistance to expanded-spectrum cephalosporins and monobactams was characterized from an Acinetobacter baumannii clinical isolate. This class C β-lactamase (named ADC-33) possessed a Pro210Arg substitution together with a duplication of an Ala residue
Rodriguez-Martinez, J.-M., Nordmann, P., Ronco, E., Poirel, L.   +3 more
openaire   +2 more sources

Determination of imipenem efflux-mediated resistance in Acinetobacter spp., using an efflux pump inhibitor

Iranian Journal of Microbiology, 2019
Background and Objectives: In recent years, reports of Acinetobacter strains resistant to all known antibiotics have caused a great concern in medical communities. Overexpression of efflux pumps is one of the major causes of resistance in bacteria.
Ghazale Amiri, Maryam Abbasi Shaye, Masoumeh Bahreini, Asghar Mafinezhad, Kiarash Ghazvini, Mohammad Reza Sharifmoghadam   +5 more
doaj   +1 more source

A degenerate PCR-based strategy as a means of identifying homologues of aminoglycoside and ß-lactam resistance genes in the gut microbiota [PDF]

, 2014
peer-reviewedBackground: The potential for the human gut microbiota to serve as a reservoir for antibiotic resistance genes has been the subject of recent discussion. However, this has yet to be investigated using a rapid PCR-based approach.
Cotter, Paul D., Fitzgerald, Gerald F, Fouhy, Fiona, Ross, R Paul, STANTON, CATHERINE   +4 more
core   +1 more source

Ventilator-associated Acinetobacter baumannii pneumonia

Indian Pediatrics, 2011
We report an outbreak of ventilator-associated pneumonia caused by carbapenem-resistant Acinetobacter baumannii in 6 infants with acute lower respiratory tract infection. Non-bronchoscopic bronchoalveolar lavage isolated A. baumannii in all these infants.
Kala, Ebenezer, Ebor Jacob G, James, Joy Sarojini, Michael, Gagandeep, Kang, Valsan Philip, Verghese   +4 more
openaire   +2 more sources

Acinetobacter infections: A growing threat in the hospital

Journal of Marine Medical Society, 2013
Acinetobacter baumannii is a Gram Negative coccobacilli implicated in causation of wide spectrum of nosocomial infections. Multidrug resistant Acinetobacter (MDR Acinetobacter) is emerging as an important cause of hospital acquired infections like ...
Ruby Chattopadhyay, Naveen Chawla, Ramesh Rao, Yamuna Jaikishan, Kainaz Sidhwa   +4 more
doaj   +1 more source

Synthesis and evaluation of troponoids as a new class of antibiotics [PDF]

, 2018
Novel antibiotics are urgently needed. The troponoids [tropones, tropolones, and α-hydroxytropolones (α-HT)] can have anti-bacterial activity. We synthesized or purchased 92 troponoids and evaluated their antibacterial activities against Staphylococcus ...
Adegboyega, Patrick, Cao, Feng, Donlin, Maureen J., Elagawany, Mohamed, Elgendy, Bahaa, Meyers, Marvin J., Murelli, Ryan P., Orth, Cari, Tavis, John E.   +8 more
core   +4 more sources

Enhanced Infection Resistance and Regenerative Healing of Titanium Implants via Peptide‐Loaded Biodegradable Coatings

Advanced Materials Technologies, EarlyView.
This study presents a new biodegradable coating for titanium implants using a natural antimicrobial peptide, caerin 1.9. Applied via solvent casting, the coating offers sustained antibacterial protection and promotes healing. Tested on 3D‐printed porous titanium scaffolds, it effectively prevented infection—including against resistant bacteria—while ...
Hejie Li, Tianfang Wang, Nicolas Soro, Guoying Ni, Meg Allom, D. İpek Kurtböke, Xiaosong Liu, Damon Kent   +7 more
wiley   +1 more source

Evaluation of the Antimicrobial Ability of Probiotics Against Nosocomial Infections by Inhibiting Ompa Gene Expression in Acinetobacter Baumannii

Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2021
Background: and Aim Acinetobacter baumannii causes various nosocomial infections and has a high antibiotic resistance. Probiotics can produce metabolites with antimicrobial properties.
Farangis Ghanipour, Razieh Nazari, Seyed Soheil Aghaee, Parvane Jafari   +3 more
doaj  

Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response

Advanced Science, EarlyView.
This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai, Mengping He, Jianya Luo, Shuang Zhou, Tengyue Zhang, Jianing Li, Zhiqiang Wang, Yuan Liu   +7 more
wiley   +1 more source