Results 51 to 60 of about 88,379 (263)

Smart Antibacterial Coatings: Harnessing Bacterial Redox Activity for Infection Control

Advanced Materials Interfaces, EarlyView.
In this study, we have shown that ceftazidime‐loaded poly(3,4‐ethylenedioxythiophene) (PEDOT@CAZ) functions as a smart, redox‐responsive antibacterial coating that couples bacterial electrical activity with localized antibiotic delivery. Shewanella oneidensis and Pseudomonas aeruginosa induced distinct redox responses in PEDOT, reflecting their ...
Abdullah, Szymon Smołka, Kamran Ayaz, Sara Shakibania, Sajida Maryam, Taral Patel, Roman Turczyn, Ewa Zabłocka‐Godlewska, Katarzyna Krukiewicz   +8 more
wiley   +1 more source

Structure and Evolution of Acinetobacter baumannii Plasmids [PDF]

Frontiers in Microbiology, 2020
Acinetobacter baumannii is an emergent bacterial pathogen that provokes many types of infections in hospitals around the world. The genome of this organism consists of a chromosome and plasmids. These plasmids vary over a wide size range and many of them have been linked to the acquisition of antibiotic-resistance genes.
Abraham D. Salgado-Camargo, Semiramis Castro-Jaimes, Rosa-Maria Gutierrez-Rios, Luis F. Lozano, Luis Altamirano-Pacheco, Jesús Silva-Sanchez, Ángeles Pérez-Oseguera, Patricia Volkow, Santiago Castillo-Ramírez, Miguel A. Cevallos   +9 more
openaire   +3 more sources

Defining bacterial species in the genomic era : insights from the genus Acinetobacter [PDF]

, 2012
Background: Microbial taxonomy remains a conservative discipline, relying on phenotypic information derived from growth in pure culture and techniques that are time-consuming and difficult to standardize, particularly when compared to the ease of modern
Loman, Nicholas J, Chan, Jacqueline, Nicholas J Loman, Chan, Jacqueline Z-m, Constantinidou, Chrystala, Loman Nicholas J, Halachev, Mihail R, Pallen, Mark J, Pallen, Mark J., Halachev Mihail R, Mihail R Halachev, Loman, Nicholas J., Pallen Mark J, Halachev, Mihail R., Jacqueline Z-M Chan, Chrystala Constantinidou, Chan Jacqueline Z-M, Constantinidou Chrystala, Mark J Pallen   +18 more
core   +1 more source

Polychip‐A High‐Throughput Droplet Microfluidics Platform for Interrogating Microbial Interactions

Advanced Science, EarlyView.
Polychip, a fully integrated droplet microfluidics platform, enables high‐throughput, single‐cell resolution screening of polymicrobial interactions. By seamlessly combining six automated microfluidics operations on a single chip, the system accelerates antimicrobial discovery by 11 to 14 times compared to traditional robotic methods.
Jeong Jae Han, Adrian Ryan Guzman, Aifen Zhou, Han Zhang, Rohit Gupte, Haemin Jung, Kaylee Delgado, Sini Skariah, Ali Sultan, Arul Jayaraman, Paul de Figueiredo, Arum Han   +11 more
wiley   +1 more source

In vitro activity of curcumin in combination with epigallocatechin gallate (EGCG) versus multidrug-resistant Acinetobacter baumannii [PDF]

, 2014
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...
Wareham, DW, Jonathan W Betts, Betts, JW, David W Wareham   +3 more
core   +1 more source

Successful treatment of extensively drug-resistant Acinetobacter baumannii ventriculitis with polymyxin B and tigecycline- a case report

Antimicrobial Resistance and Infection Control, 2018
Background Acinetobacter baumannii nosocomial ventriculitis/meningitis, especially those due to drug-resistant strains, has substantially increased over recent years.
Wei Guo, Shao-Chun Guo, Min Li, Li-Hong Li, Yan Qu   +4 more
doaj   +1 more source

Mesoporous Catalytic‐Adsorptive Nanoregulator Orchestrates Biofilm eDNA/LPS Disassembly and TLR9/TLR4 Immune Reprogramming to Resolve Diabetic Foot Infections

Advanced Science, EarlyView.
Chronic diabetic wounds are hindered by a “dual trap” of biofilm resistance and hyperinflammation. A mesoporous catalytic‐adsorptive nano‐regulator is developed to dismantle this barrier through simultaneous eDNA degradation and LPS sequestration. By silencing TLR4/9‐mediated signaling, the platform clears resilient pathogens and reprograms the immune ...
Junfeng Song, Yang Song, Xirui Huang, Xingjin Li, Lifei Gao, Yixiang Wang, Tianbao Zhu, Xiaomin Li, Shuai Wang, Tiancong Zhao, Dongyuan Zhao   +10 more
wiley   +1 more source

Rapid Multiplex Antimicrobial Resistance Profiling and Bacterial Identification by LAP‐MALDI Mass Spectrometry Biotyping

Advanced Science, EarlyView.
Liquid atmospheric pressure matrix‐assisted laser desorption/ionization (LAP‐MALDI) mass spectrometry (MS) provides multiplexed biotyping of microbial cultures using a fast and simple workflow. This is demonstrated for clinically relevant bacteria, resulting in accurate antimicrobial resistance (AMR) detection, speciation by MS/MS sequencing and ...
Lily R. Adair, Shabnam Iyer, Ian M. Jones, Rainer Cramer   +3 more
wiley   +1 more source

Treatment of Acinetobacter baumannii

, 2023
Acinetobacter baumannii is a Priority 1 pathogen under the WHO list for research and discovery of new antibiotics. The epidemiology of the pathogen suggests its relevance as an important “healthcare-associated” pathogen—with the most common clinical syndrome being ventilator-associated pneumonia.
Anup R. Warrier, Sneha Radha
openaire   +1 more source

Extended-Spectrum Cephalosporinase in Acinetobacter baumannii [PDF]

Antimicrobial Agents and Chemotherapy, 2010
ABSTRACT An AmpC-type β-lactamase conferring high-level resistance to expanded-spectrum cephalosporins and monobactams was characterized from an Acinetobacter baumannii clinical isolate. This class C β-lactamase (named ADC-33) possessed a Pro210Arg substitution together with a duplication of an Ala residue
Rodriguez-Martinez, J.-M., Nordmann, P., Ronco, E., Poirel, L.   +3 more
openaire   +2 more sources