Results 41 to 50 of about 103,755 (281)

A transcriptional regulatory mechanism finely tunes the firing of type VI secretion system in response to bacterial enemies [PDF]

, 2017
The ability to detect and measure danger from an environmental signal is paramount for bacteria to respond accordingly, deploying strategies that halt or counteract potential cellular injury and maximize survival chances. Type VI secretion systems (T6SSs)
Feldman, Mario F, Lazzaro, Martina, Vescovi, Eleonora Garcia   +2 more
core   +2 more sources

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Positron Emission Tomography Imaging of Bacterial Infections With an Enterobactin Analog to Monitor Treatment Efficacy With a Catechol Antibiotic

Angewandte Chemie, EarlyView.
Synopsis. The [68Ga]GaIII‐TREN‐CAM radiochelate selectively accumulates in Gram‐negative sites of infection and noninvasively monitors treatment response a siderophore antibiotic. ABSTRACT Positron emission tomography (PET) is an emerging tool under clinical investigation for the detection of bacterial infections.
M. Andrey Joaqui‐Joaqui, Phuong Nguyen Tran, Axia Marlin, Fiona Armstrong‐Pavlik, Minhua Cao, Valérie C. Pierre, Eszter Boros   +6 more
wiley   +2 more sources

Acinetobacter Species: Phenotypic Characterization And Antimicrobial Resistance

Journal of Nobel Medical College, 2013
Background: Acinetobacter species is ubiquitous, aerobic gram-negative coccobacilli that are now emerging as an important nosocomial pathogen. Objectives: The present study was designed to know the prevalence of Acinetobacter in various clinical ...
Medhabi Shrestha, Basuda Khanal
doaj   +1 more source

Clinical and in vitro efficacy of colistin plus vancomycin and rifampin against colistin-resistant Acinetobacter baumannii causing ventilator-associated pneumonia [PDF]

, 2017
We present the case of a patient with ventilator-associated pneumonia (VAP) caused by a pan-resistant Acinetobacter baumannii successfully treated with the combination colistin plus vancomycin plus rifampin, whose in vitro activity was investigated by ...
Cipolla, Alessia, Falcone, Marco, Mastroianni, Claudio Maria, Oliva, Alessandra, Venditti, Mario, Vullo, Vincenzo   +5 more
core   +1 more source

Evaluation of the Coverage of 3 Antibiotic Regimens for Neonatal Sepsis in the Hospital Setting Across Asian Countries. [PDF]

, 2020
Importance: High levels of antimicrobial resistance in neonatal bloodstream isolates are being reported globally, including in Asia. Local hospital antibiogram data may include too few isolates to meaningfully examine the expected coverage of antibiotic ...
Agarwal, R, Bielicki, JA, Cromwell, DA, Heath, PT, Sharland, M, Turner, P, Walker, AS   +6 more
core   +3 more sources

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Previous Antibiotic Exposure and Antimicrobial Resistance Patterns of Acinetobacter spp. and Pseudomonas aeruginosa Isolated from Patients with Nosocomial Infections

Balkan Medical Journal, 2017
Background: The alarming spread of antibiotic-resistant bacteria causing healthcare-associated infections has been extensively reported in recent medical literature.
Zorana M. Djordjevic, Marko M. Folic, Slobodan M. Jankovic   +2 more
doaj   +1 more source

Experimental Models of Acinetobacter Infection [PDF]

, 2008
The use of animals as models for microbiological infections is a fundamental part of infectious disease research. The intent for the use of animals as models of disease is to establish an infection that mimics that seen in humans (Druilhe et al., 2002). The goal is to seek how the infection develops, and by what the infection can be thwarted.
Joly-Guillou, Marie-Laure, Wolff, Michel
openaire   +2 more sources

NIR‐Activated Ag2S Quantum Dots for Efficient Broad‐Spectrum Antibacterial and Biofilm Disruption

Advanced Materials Interfaces, EarlyView.
This study presents a novel non‐antibiotic strategy leveraging NIR‐activated Ag2S QDs for synergistic PTT/PDT. The platform degrades the protective extracellular matrix via localized hyperthermia, facilitating deep penetration and ROS‐induced oxidative damage.
Rui Yao, Peiqing Sun, Yaxin Chen, Zhijie Lei, Li Wang, Jianglin Yu, Ying Liu, Wusimanjiang Hailipitimu, Wei Wei, Jing Zhao, Xusheng Qiu   +10 more
wiley   +1 more source