Results 11 to 20 of about 15,427 (288)

The effects of acitretin on insulin resistance, glucose metabolism, and lipid levels in patients with psoriasis

Indian Journal of Dermatology, 2022
Context: Acitretin increases serum lipids. Data on its effects on insulin resistance and glucose metabolism are sparse and contradicting. Aims: The aim of this study is to investigate the effects of acitretin on insulin resistance, glucose metabolism ...
Satnam Singh Sachdev, Adawiyah Jamil, Preamala Gunabalasingam, Najeeb Ahmad Safdar   +3 more
doaj   +2 more sources

The Inflammatory Factor SNP May Serve as a Promising Biomarker for Acitretin to Alleviate Secondary Failure of Response to TNF-a Monoclonal Antibodies in Psoriasis

Frontiers in Pharmacology, 2022
Psoriasis is a common immune-mediated inflammatory skin disease. Although biological agents have achieved good clinical efficacy in the treatment of moderate-to-severe psoriasis, the phenomenon of secondary non-response (SNR) has been gradually ...
Lanmei Lin, Yilun Wang, Xiaonian Lu, Tianxiao Wang, Qunyi Li, Runnan Wang, Jinfeng Wu, Jinhua Xu, Juan Du   +8 more
doaj   +2 more sources

Acitretin Promotes the Differentiation of Myeloid-Derived Suppressor Cells in the Treatment of Psoriasis

Frontiers in Medicine, 2021
Increased numbers of myeloid-derived suppressor cells (MDSCs) are involved in the development of psoriasis. Acitretin is used to treat psoriasis by regulating the proliferation and differentiation of keratinocytes, but little is known about the effect of
Panpan Liu, Panpan Liu, Panpan Liu, Cong Peng, Cong Peng, Cong Peng, Xiang Chen, Xiang Chen, Xiang Chen, Xiang Chen, Lisha Wu, Lisha Wu, Lisha Wu, Mingzhu Yin, Mingzhu Yin, Mingzhu Yin, Jie Li, Jie Li, Jie Li, Qunshi Qin, Qunshi Qin, Qunshi Qin, Yehong Kuang, Yehong Kuang, Yehong Kuang, Wu Zhu, Wu Zhu, Wu Zhu, Wu Zhu   +28 more
doaj   +2 more sources

HLA-DQA1 and DQB1 Alleles are Associated with Acitretin Response in Patients with Psoriasis

Frontiers in Bioscience-Landmark, 2022
Background: Psoriasis vulgaris is an immune-mediated inflammatory skin disease. Although the pathogenesis of psoriasis is unclear, genetic susceptibility, such as HLA-C*06:02, is believed to be a major risk factor.
Xingchen Zhou, Yijing He, Yehong Kuang, Wangqing Chen, Wu Zhu   +4 more
doaj   +2 more sources

Reductive Effect of Acitretin on Blood Glucose Levels in Chinese Patients With Psoriasis

Frontiers in Medicine, 2021
Background: Psoriasis is a skin condition associated with increased risks of developing metabolic diseases, such as diabetes and hyperlipidaemia. Retinoid drugs, including acitretin, are commonly used to treat psoriasis due to its low cost and tolerable ...
Hua Qian, Hua Qian, Hua Qian, Yehong Kuang, Yehong Kuang, Juan Su, Juan Su, Menglin Chen, Menglin Chen, Xiang Chen, Xiang Chen, Chengzhi Lv, Wangqing Chen, Wangqing Chen, Wu Zhu, Wu Zhu   +15 more
doaj   +2 more sources

Efficacy and Safety of Tripterygium Wilfordii Glycoside Tablets Combined with Acitretin Capsules in the Treatment of Moderate to Severe Plaque Psoriasis: A Randomized Controlled Trial

Applied Bionics and Biomechanics, 2022
Objective. To probe into the clinical efficacy of tripterygium wilfordii glycoside (TWGs) tablets combined with acitretin capsules in the treatment of patients with moderate to severe plaque psoriasis (MSPP). Methods.
Qinghui Fu, Yunjie Zhu, Yiqi Fang, Changbo Dai   +3 more
doaj   +2 more sources

In Vitro and Ex Vivo Evaluation of Fluocinolone Acetonide–Acitretin-Coloaded Nanostructured Lipid Carriers for Topical Treatment of Psoriasis

Gels, 2022
Psoriasis is chronic autoimmune disease that affects 2–5% of the global population. Fluocinolone acetonide (FLU) and acitretin (ACT) are widely used antipsoriatic drugs that belong to BCS classes II and IV, respectively.
Hassan Raza, Shefaat Ullah Shah, Zakir Ali, Atif Ullah Khan, Irfa Basharat Rajput, Arshad Farid, Mohammed Al Mohaini, Abdulkhaliq J. Alsalman, Maitham A. Al Hawaj, Saima Mahmood, Abid Hussain, Kifayat Ullah Shah   +11 more
doaj   +2 more sources

Case Report: Successful Treatment of Cutaneous Squamous Cell Carcinoma in Three Patients With a Combination of Acitretin and Clarithromycin

Frontiers in Oncology, 2021
Few studies have evaluated acitretin as a primary treatment for cutaneous squamous cell carcinoma (CSCC). We report, for the first time, three cases of CSCC successfully treated with acitretin and clarithromycin.
Yan Zhao, Yanting Zhu, Haiqing Wang, Chao Ji   +3 more
doaj   +2 more sources

A case of classic adult pityriasis rubra pilaris successfully treated with a combination of acitretin and ustekinumab: A case report

SAGE Open Medical Case Reports, 2022
Classic adult pityriasis rubra pilaris is a severe papulosquamous disease that tends to resolve in 3–5 years but can have a devastating impact on patients while active.
Celina DeBiasio, Janelle Cyr, Yasmine Ayroud, Steven J Glassman   +3 more
doaj   +2 more sources

Role and mechanism of matrine alone and combined with acitretin for HaCaT cells and psoriasis-like murine models

Chinese Medical Journal, 2019
. Background:. Acitretin and matrine have been used in the treatment of psoriasis in China. This study was designed to investigate the role and related mechanisms of matrine alone and in combination with acitretin in the treatment of psoriasis in vitro ...
Wei-Wei Jiang, Yi-Meng Wang, Xiao-Yu Wang, Qian Zhang, Si-Man Zhu, Chun-Lei Zhang, Li-Shao Guo   +6 more
doaj   +2 more sources