Results 41 to 50 of about 7,011 (197)

Reducing Exposure Before Birth: An Interrupted Time Series Study of Prenatal Exposure to Fetotoxic Medications Under Risk Management Plans in Canada

Clinical Pharmacology &Therapeutics, EarlyView.
Canada's 2009 risk management plan (RMP) framework has not been evaluated for prenatal exposure impact. Conversely, widely used drugs such as nonsteroidal anti‐inflammatory drugs (NSAIDs) lack RMPs. We assessed first‐trimester exposure to RMP‐regulated medications following regulatory interventions and to NSAIDs following safety publications.
Nahiyan Saiyara Khan, Odile Sheehy, Lisiane Freitas Leal, Vanina Tchuente, Anick Bérard   +4 more
wiley   +1 more source

Mutations in CERS3 Gene Underlies a Case of Autosomal Recessive Congenital Ichthyosis

罕见病研究, 2023
Autosomal recessive congenital ichthyosis caused by CERS3 mutations is extremely rare in clinical practice. We recently identified a family of autosomal recessive congenital ichthyosis and performed multigene exome sequencing for hereditary skin diseases
LIU Juan, MO Ran, LIU Yihe, HUANG Xin, GAO Meng, YANG Yong, CHEN Zhiming   +6 more
doaj   +1 more source

Acitretin Use in Dermatology

, 2017
Background: Acitretin has been used for the treatment of severe psoriasis for over 20 years. Objective: The current project was conceived to optimise patient care by recognising the role acitretin can play in the treatment of patients with psoriasis and ...
Lyn C. Guenther, John Toole, Charles W. Lynde, Rod Kunynetz, Catherine Zip, Ronald Vender, R. Gary Sibbald   +6 more
core   +1 more source

Fixed tapering dosage of acitretin in patients with psoriasis: A short-term analysis of clinical efficacy and its effects on biochemical parameters

Indian Journal of Dermatology, 2019
Background: Acitretin is a widely used systemic retinoid in the treatment of psoriasis. Dosage of acitretin in not weight adjusted due to certain interindividual variations.
Varadraj V Pai, Diksha Phadke, Pankaj Shukla, Krupeksha Naik   +3 more
doaj   +1 more source

JAK Inhibitors in Psoriatic–Atopic Dermatitis Overlap: A Four‑Case Series

JEADV Clinical Practice, EarlyView.
ABSTRACT Overlap between psoriasis and atopic dermatitis (AD) poses diagnostic and therapeutic challenges; monoclonal antibodies targeting a single axis may improve one component while worsening the other [1]. Janus kinase (JAK) inhibitors act pleiotropically and may provide simultaneous control of psoriatic and eczematous inflammation [2].
Eleonora Bongiovanni, Francois Rosset, Isotta Giunipero di Corteranzo, Lorenzo Bellando, Rebecca Senetta, Simone Ribero, Pietro Quaglino   +6 more
wiley   +1 more source

Small intestine perforation in a 58-year-old man with Darier disease after 25 months of oral acitretin therapy

Dermatologica Sinica, 2014
Darier disease is a rare autosomal dominant disease characterized by abnormal keratinization of the epidermis, mucosa, and nails. Acitretin, an aromatic form of tretinoin, is widely prescribed in the treatment of Darier disease.
Yi-Hao Wang, Dino Tsai
doaj   +1 more source

A case of classic adult pityriasis rubra pilaris successfully treated with a combination of acitretin and ustekinumab: A case report

SAGE Open Medical Case Reports, 2022
Classic adult pityriasis rubra pilaris is a severe papulosquamous disease that tends to resolve in 3–5 years but can have a devastating impact on patients while active.
Celina DeBiasio, Janelle Cyr, Yasmine Ayroud, Steven J Glassman   +3 more
doaj   +1 more source

Juvenile Mycosis Fungoides: A Multicenter Retrospective Italian Study

JEADV Clinical Practice, EarlyView.
This multicenter retrospective study included 29 juvenile mycosis fungoides (JMF) patients from five Italian centres with confirmed histopathological diagnosis. most often presents with hypopigmented/classic variants and CD8+ phenotype. Early‐onset cases ( < 14 years) show better long‐term outcomes.
Andrea Michelerio, Gabriele Roccuzzo, Iria Neri, Alessandro Pileri, Alessandro Svizzero, Maria Beatrice De Felici Del Giudice, Vieri Grandi, Pietro Quaglino, Valeria Brazzelli   +8 more
wiley   +1 more source

Acitretin-induced subungual hemorrhage

, 2007
Bu çalışma, 12-16 Ekim 2005 tarihlerinde Londra[Birleşik Krallık]'da düzenlenen 14. Congress of The European Academy of Dermatology and Venereology'de poster olarak sunulmuştur.A 20-year-old woman with a 2-year history of histologically confirmed ...

core   +1 more source

Early Acitretin Therapy in a Patient With Harlequin Ichthyosis

JEADV Clinical Practice, EarlyView.
ABSTRACT Harlequin ichthyosis (HI) is a rare, severe congenital disorder of keratinization caused by pathogenic variants in the ABCA12 gene resulting in thick, hyperkeratotic plates, deep fissures, and characteristic facial and limb abnormalities.
Orasa Sukmark, Parith Wongkittichote, Sanchawan Wittayakornrerk   +2 more
wiley   +1 more source