Results 51 to 60 of about 11,680 (228)

Frizzled-related proteins 4 (SFRP4) rs1802073G allele predicts the elevated serum lipid levels during acitretin treatment in psoriatic patients from Hunan, China [PDF]

open access: yesPeerJ, 2018
Background Acitretin is a second-generation synthetic retinoid, and is widely used for treating the severe psoriasis vulgaris. However, it should be chosen with caution for its cardiovascular risk, and it is reported that acitretin may increase the serum
Xingchen Zhou   +9 more
doaj   +2 more sources

Circulating microRNA profile unveils mechanisms of action of acitretin for psoriasis vulgaris

open access: yesBioengineered, 2021
Psoriasis vulgaris is a common chronic and recurrent inflammatory skin disease. In clinical practice, acitretin is the first-line treatment drug for psoriasis vulgaris.
Lin Chen   +6 more
semanticscholar   +1 more source

Assessment by HPLC of the degradation behavior of acitretin under hydrolytic, oxidative, photolytic and thermal stress conditions

open access: yesActa Pharmaceutica Sinica B, 2014
Acitretin is a photosensitive oral retinoid with very limited data available on its degradation. The official HPLC method for acitretin determination was insufficient to resolve the degradation products generated during stability studies.
Pawan K. Porwal, Neeraj Upmanyu
doaj   +1 more source

Shotgun lipidomics of liver and brain tissue of Alzheimer’s disease model mice treated with acitretin

open access: yesScientific Reports, 2021
Alzheimer’s disease (AD) is a very frequent neurodegenerative disorder characterized by an accumulation of amyloid-β (Aβ). Acitretin, a retinoid-derivative and approved treatment for Psoriasis vulgaris, increases non-amyloidogenic Amyloid-Precursor ...
A. Lauer   +11 more
semanticscholar   +1 more source

Impact of Adverse Events Associated With Acitretin Treatment of Moderate-to-Severe Plaque Psoriasis: Based on an Observational, Single-Center Study in Shanghai, China

open access: yesInternational Journal of Dermatology and Venerology, 2023
Objective:. Acitretin is a widely used systemic retinoid that is to treat psoriasis but has significant variations in efficacy and adverse events (AEs) among individuals. This study aimed to determine the impact of AEs associated with acitretin treatment
Xiao-Yuan Zhong   +8 more
doaj   +1 more source

Small intestine perforation in a 58-year-old man with Darier disease after 25 months of oral acitretin therapy

open access: yesDermatologica Sinica, 2014
Darier disease is a rare autosomal dominant disease characterized by abnormal keratinization of the epidermis, mucosa, and nails. Acitretin, an aromatic form of tretinoin, is widely prescribed in the treatment of Darier disease.
Yi-Hao Wang, Dino Tsai
doaj   +1 more source

Acitretin-Induced Repigmentation of Gray Hair: A Case Report

open access: yesCureus
Acitretin is an oral retinoid with alopecia as a possible adverse effect. However, repigmentation of the hair color after acitretin is not a well-documented phenomenon.
Eunice Y Chow, T. Salopek
semanticscholar   +1 more source

Detection of acitretin transport across the BBB.

open access: yes, 2014
(A) After 48 hours the amount of acitretin transported across the brain endothelial cell barrier was measured by HPLC. Various concentrations were used to calculate the permeability coefficient of acitretin (Papp (acitretin)).
Kristina Endres (532488)   +5 more
core   +1 more source

Combined Abrocitinib and Acitretin Therapy for Darier’s Disease: A Case Report

open access: yesClinical, Cosmetic and Investigational Dermatology
Darier’s disease (DD) is a rare chronic keratinizing skin disease characterized by dyskeratosis of epidermal cells. We report a case of DD with a medical history spanning over 20 years and recurring symptoms.
Hui Ye   +5 more
semanticscholar   +1 more source

Successful Treatment of Refractory Lichen Amyloidosus With Dupilumab

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Lichen amyloidosis (LA) is a chronic, pruritic dermatosis with papillary dermal amyloid deposition. Standard therapies often fail, and most reports of dupilumab in LA involve patients with concomitant atopic dermatitis. We report a 32‐year‐old man with refractory, non‐atopic LA who had failed topical corticosteroids, tacrolimus, phototherapy ...
Sohrab Elahwiesy   +5 more
wiley   +1 more source

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