Results 61 to 70 of about 7,011 (197)
Update on Combination Treatment with Acitretin for Generalized Psoriasis
, 2010 Acitretin (Soriatane) is the only systemic retinoid approved for the treatment of psoriasis. Unlike all other anti-psoriasis systemic agents, acitretin is the only clinically nonimmunosuppressive systemic medication that works primarily by enhancing ...
Tina Bhutani
core +1 more source
Dermatologic Toxicities Associated With Novel Pan‐RAS/RAF Inhibitors
Journal of Cutaneous Pathology, EarlyView.ABSTRACT Background The mitogen‐activated protein kinase (MAPK) pathway plays a key role in cell‐cycle regulation and tumor progression in cancer. Dermatologic toxicities (DTs) to newer pan‐RAS (RMC‐6236) and pan‐RAF (LXH254/naporafenib) inhibitors are emerging.
Lin J. He +11 more
wiley +1 more source
Severe and prolonged liver damage in pityriasis rubra pilaris treated with acitretin: a case report
, 2022 Acitretin is a systemic retinoid that is used in dermatology for treatment of various inflammatory and especially hyperkeratotic diseases. Elevation of liver enzymes may occur occasionally but normally resolves spontaneously, at the latest after ...
Goebeler, Matthias +4 more
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A comparative analysis of acitretin and methotrexate in the treatment of lichen planus
Turkderm Turkish Archives of Dermatology and VenereologyBackground and Design: Lichen planus (LP) is a common inflammatory dermatosis affecting people of all ages. Acitretin is one of the firstline systemic treatments; however, certain circumstances limit its use and encourage the search for alternative ...
Özge Sevil Karstarlı Bakay +1 more
doaj +1 more source
S1 Guideline: Therapy of generalized pustular psoriasis
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary The S1 guideline “Therapy of generalized pustular psoriasis (GPP)” is a German guideline developed in accordance with the criteria of the AWMF. The full version addresses clinical presentation, pathogenesis, diagnosis and differential diagnosis, comorbidities, and therapy.
Rotraut Mößner +17 more
wiley +1 more source
, 2022 The efficacy of 5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) on invasive cutaneous squamous cell carcinoma (cSCC) remains to be improved due to the limited penetration of this treatment.
Ye, Ting Lu +7 more
core +1 more source
Systemic Treatment and Outcome in Erythrodermic Psoriasis: A Retrospective Multicenter Study
International Journal of Dermatology, EarlyView.This multicentre real‐world study illustrates the heterogeneity of systemic treatment approaches in erythrodermic psoriasis (EP) in Bavaria, Germany. Adverse events were more frequently observed with conventional therapies, whereas biologic therapies showed favorable outcomes.
Julian Kögel +15 more
wiley +1 more source
Mapping malignant T‐cell states and immune circuits in Sézary syndrome by single‐cell analysis
Journal of the European Academy of Dermatology and Venereology, EarlyView.Peripheral blood single‐cell RNA‐seq from leukaemic CTCL defined three malignant T‐cell programmes: MTC CM, MTC Reg and MTC E/EM, each with distinct features and candidate vulnerabilities. For example, inferred immune circuits highlighted actionable IL‐10/JAK–TYK2–STAT3 signalling, KIR–MHC I inhibitory interactions and myeloid/B‐cell inflammatory and ...
Beth A. Childs +6 more
wiley +1 more source
A study on the management of hidradenitis suppurativa with retinoids and surgical excision
Indian Journal of Dermatology, 2011 Background: Hidradenitis suppurativa is a chronic skin condition involving the apocrine glandular zones. Affected patients may present with acute abscesses, but the condition often progresses to a chronic state with persistent pain, sepsis, sinus tract ...
Neerja Puri, Ashutosh Talwar
doaj +1 more source