Results 1 to 10 of about 7,011 (197)

Acitretin modulates HaCaT cells proliferation through STAT1- and STAT3-dependent signaling

open access: yesSaudi Pharmaceutical Journal, 2017
Acitretin has been a valuable option for the treatment of psoriasis, however, the molecular events of acitretin leading to the normalization of keratinocytes differentiation on psoriasis patients have not been fully explored. To investigate whether there
Xuan Qin   +8 more
exaly   +4 more sources

Acitretin

open access: yesTurkderm Turkish Archives of Dermatology and Venereology, 2022
Acitretin is a synthetic retinoid and an active metabolite of etretinate. It shows its action in psoriasis treatment by suppressing proliferation and enhancing the differentiation of keratinocytes.
Nihal Kundakçı
doaj   +4 more sources

Acitretin in dermatology

open access: yesApollo Medicine, 2023
Introduction/Background: Acitretin is a second-generation systemic retinoid. Its clinical applications are virtually exclusively limited to dermatology. It has anti-inflammatory, antiproliferative, and antikeratinizing effects.
Rashmi Sarkar, Amit Kumar Meena
doaj   +2 more sources

Effects of Acitretin Treatment on Hearing in Patients with Psoriasis Vulgaris

open access: yesThe Turkish Journal of Ear Nose and Throat, 2022
Objective: In this study, we aimed to compare the hearing thresholds and outer hair cell functions of patients with psoriasis vulgaris (PV) with healthy individuals and to investigate the ototoxic effects of acitretin treatment (AT) in patients with PV ...
Başak Mutlu   +4 more
doaj   +2 more sources

Assessment by HPLC of the degradation behavior of acitretin under hydrolytic, oxidative, photolytic and thermal stress conditions

open access: yesActa Pharmaceutica Sinica B, 2014
Acitretin is a photosensitive oral retinoid with very limited data available on its degradation. The official HPLC method for acitretin determination was insufficient to resolve the degradation products generated during stability studies.
Neeraj Upmanyu
exaly   +3 more sources

Reductive Effect of Acitretin on Blood Glucose Levels in Chinese Patients With Psoriasis

open access: yesFrontiers in Medicine, 2021
Background: Psoriasis is a skin condition associated with increased risks of developing metabolic diseases, such as diabetes and hyperlipidaemia. Retinoid drugs, including acitretin, are commonly used to treat psoriasis due to its low cost and tolerable ...
Hua Qian   +15 more
doaj   +1 more source

Acitretin Promotes the Differentiation of Myeloid-Derived Suppressor Cells in the Treatment of Psoriasis

open access: yesFrontiers in Medicine, 2021
Increased numbers of myeloid-derived suppressor cells (MDSCs) are involved in the development of psoriasis. Acitretin is used to treat psoriasis by regulating the proliferation and differentiation of keratinocytes, but little is known about the effect of
Panpan Liu   +28 more
doaj   +1 more source

The effects of acitretin on insulin resistance, glucose metabolism, and lipid levels in patients with psoriasis

open access: yesIndian Journal of Dermatology, 2022
Context: Acitretin increases serum lipids. Data on its effects on insulin resistance and glucose metabolism are sparse and contradicting. Aims: The aim of this study is to investigate the effects of acitretin on insulin resistance, glucose metabolism ...
Satnam Singh Sachdev   +3 more
doaj   +1 more source

The effects of acitretin on ovarian reserve: An experimental study in rats

open access: yesTurkderm Turkish Archives of Dermatology and Venereology, 2022
Background and Design: Acitretin is widely used on many dermatological diseases. No adequate studies have evaluated its effects on ovarian reserve. Thus, this experimental study aimed to investigate the possible effects of acitretin on ovarian reserve by
Münevver Güven   +4 more
doaj   +1 more source

Acitretin

open access: yesReactions Weekly, 2016
Lichen planus (LP) is a chronic inflammatory dermatosis of unknown etiology characterized by pruritic violaceous papules. Here, we share our experience of a long standing case of disseminated hypertrophic LP treated with oral acitretin.
Elaine J. Lin   +3 more
  +6 more sources

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